Sandbox Reserved 342: Difference between revisions
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== ''' | == '''XANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE''' == | ||
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= | =Structure= | ||
PRTase structures fall into two groups, type I and Type II<ref name="Vos"/>. | |||
XGTPase has a conserved sequence, 85-IVIDDLVDTG-94, which is called the PRib-PP (5-phospho-a-D-ribosyl-1-pyrophosphate) binding site<ref name="Vos"/>. This binding site features two adjacent acidic residues, which are surrounded by hydrophobic residues<ref name="Vos"/>. There s five-stranded b-sheet surrounded by three or four a-helices that creates a conserved structural core containing the PRib-PP binding site<ref name="Vos"/> | |||
=Function= | |||
= | |||
XGRT is an enzyme that catalyzes the conversion of guanine, xanthine, and sometimes hypoxanthine, to GMP, XMP, and IMP <ref name="Vos"/>. | XGRT is an enzyme that catalyzes the conversion of guanine, xanthine, and sometimes hypoxanthine, to GMP, XMP, and IMP <ref name="Vos"/>. | ||
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<scene name='Sandbox_Reserved_342/Trial/1'>TextToBeDisplayed</scene>=MECHANISM= | <scene name='Sandbox_Reserved_342/Trial/1'>TextToBeDisplayed</scene>=MECHANISM= | ||
== | ==Recognition== | ||
== | ==Catalysis== | ||
Magnesium and other divalent cations are necessary for catalysis<ref name="Vos"/>. | Magnesium and other divalent cations are necessary for catalysis<ref name="Vos"/>. | ||
= | =Importance= | ||
<Structure load='1a96' size='300' frame='true' align='right' caption='Insert caption here' scene='Insert optional scene name here' /> | <Structure load='1a96' size='300' frame='true' align='right' caption='Insert caption here' scene='Insert optional scene name here' /> | ||
=''' | ='''Additional Resources'''= | ||
=References= | =References= | ||
<references/> | <references/> | ||