Sandbox Reserved 342: Difference between revisions
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__TOC__ | __TOC__ | ||
=Introduction= | =Introduction= | ||
Xanthine-guanine Phosphoribosyltansferase (XGPRT) is one of three PRTases that are part of the purine salvage pathway in Escherichia coli <ref name="Vos"> PMID:9743633 </ref>. | Xanthine-guanine Phosphoribosyltansferase (XGPRT) is one of three purine phosphoribosyltransferases (PRTases) that are part of the purine salvage pathway in Escherichia coli <ref name="Vos"> PMID:9743633 </ref>; the other two PRTases in the pathway are HPRT and APRT<ref name="Vos"/>. | ||
=STRUCTURE= | =STRUCTURE= | ||
=FUNCTION= | =FUNCTION= | ||
XGRT is an enzyme that catalyzes the conversion of guanine, xanthine, and sometimes hypoxanthine, to GMP, XMP, and IMP <ref name="Vos"/>. | |||
=MECHANISM= | <scene name='Sandbox_Reserved_342/Trial/1'>TextToBeDisplayed</scene>=MECHANISM= | ||
==RECOGNITION== | ==RECOGNITION== | ||
==CATALYSIS== | ==CATALYSIS== | ||
Magnesium and other divalent cations are necessary for catalysis<ref name="Vos"/>. | |||
=IMPORTANCE= | =IMPORTANCE= | ||
<Structure load='1a96' size='300' frame='true' align='right' caption='Insert caption here' scene='Insert optional scene name here' /> | <Structure load='1a96' size='300' frame='true' align='right' caption='Insert caption here' scene='Insert optional scene name here' /> | ||
Revision as of 03:56, 3 April 2011
| This Sandbox is Reserved from January 10, 2010, through April 10, 2011 for use in BCMB 307-Proteins course taught by Andrea Gorrell at the University of Northern British Columbia, Prince George, BC, Canada. |
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| 1a96, resolution 2.00Å () | |||||||||
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| Ligands: | , , , | ||||||||
| Gene: | GPT (Escherichia coli) | ||||||||
| Activity: | Xanthine phosphoribosyltransferase, with EC number 2.4.2.22 | ||||||||
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| Resources: | FirstGlance, OCA, RCSB, PDBsum | ||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||
Xanthine-guanine PhosphoribosyltransferaseXanthine-guanine Phosphoribosyltransferase
IntroductionIntroduction
Xanthine-guanine Phosphoribosyltansferase (XGPRT) is one of three purine phosphoribosyltransferases (PRTases) that are part of the purine salvage pathway in Escherichia coli [1]; the other two PRTases in the pathway are HPRT and APRT[1].
STRUCTURESTRUCTURE
FUNCTIONFUNCTION
XGRT is an enzyme that catalyzes the conversion of guanine, xanthine, and sometimes hypoxanthine, to GMP, XMP, and IMP [1].
=MECHANISM=
RECOGNITIONRECOGNITION
CATALYSISCATALYSIS
Magnesium and other divalent cations are necessary for catalysis[1].
IMPORTANCEIMPORTANCE
|