Simvastatin Synthase: Difference between revisions

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{{STRUCTURE_3hle |  PDB=3hle  |  SCENE=  }}  
{{STRUCTURE_3hle |  PDB=3hle  |  SCENE=  }}  
==Introduction==
==Introduction==
[[Image:svs.jpg]]'''Simvastatin synthase''' (LovD) is a 46 kDa acyltransferase found in the lovastatin biosynthetic pathway and catalyzes the final step of lovastatin biosynthesis<ref name="paper4">PMID:
[[align="left" Image:svs.jpg]]'''Simvastatin synthase''' (LovD) is a 46 kDa acyltransferase found in the lovastatin biosynthetic pathway and catalyzes the final step of lovastatin biosynthesis<ref name="paper4">PMID:
17113998</ref>. Pictured here is the D5 mutant complexed with monacolin J acid (Figure 1).
17113998</ref>. Pictured here is the D5 mutant complexed with monacolin J acid (Figure 1).


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Eric Ginter, David Canner, Michal Harel, Alexander Berchansky