Sandbox Reserved 316: Difference between revisions
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LovD has <scene name='Sandbox_Reserved_316/Cysteines/1'>nine cysteines</scene> at the following positions: C40, C49, C60, C72, C89, C216, C266, C380, and C395<ref name="paper3">PMID:18988191</ref>. | LovD has <scene name='Sandbox_Reserved_316/Cysteines/1'>nine cysteines</scene> at the following positions: C40, C49, C60, C72, C89, C216, C266, C380, and C395<ref name="paper3">PMID:18988191</ref>. | ||
== | ==Significance== | ||
As simvastatin is an active pharmaceutical ingredient in the cholesterol-lower drug Zocor®, | As simvastatin is an active pharmaceutical ingredient in the cholesterol-lower drug Zocor®, its efficient synthesis from lovastatin, via LovD is intensely pursued <ref name="paper1">PMID:17277201</ref>. | ||
==References== | ==References== | ||
<references/> | <references/> |