Sandbox Reserved 200: Difference between revisions

No edit summary
No edit summary
Line 13: Line 13:




Both dimers conserve the structure of the two monomers except for the conformation at the hinge loop.  The hinge loop is the location where the two monomers connect acting like the hinge of a door.<ref name="liul"/>  In the major dimer, the hinge loop is composed of residues 112-115. In the minor dimer, the hinge loop is composed of residues 16-22.<ref name="liul"/>  The most important component of the hinge loops is Ala19.  <scene name='Sandbox_Reserved_200/Minor_dimer_hinge/1'>Ala19</scene> is the reason why the hinge loops are so flexible . This flexibility allows the dimers to adopt different orientations.<ref name="liu98"/>   
Both dimers conserve the structure of the two monomers except for the conformation at the hinge loops.  The  
<scene name='Sandbox_Reserved_200/Minor_dimer/3'>hinge loop</scene> is the location where the two monomers connect acting like the hinge of a door.<ref name="liul"/>  The most important component of the hinge loops is Ala19.  <scene name='Sandbox_Reserved_200/Minor_dimer_hinge/1'>Ala19</scene> gives these hinges their flexibility. This flexibility allows the dimers to adopt different orientations.<ref name="liu98"/>   




Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA, Lexi Gehring, R. Jeremy Johnson, Jaime Prilusky