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== Prion Protein (2HH0) ==
== Prion Protein (2HH0) ==
2HH0 is a prion protein that manifests in bovine(cattle) and can lead to degenerative central nervous system tissues. The word “prion” is derived from “protein + infection.”  Prions were discovered in 1997 by Stanley B. Prusiner of the University of California.(1) They are infected proteins and may lay dormant for many years before they activate and cause damage to the brain an spinal cord. <ref name="Insert name">McCord JM, Fridovich I. Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein). J Biol Chem. 1969 Nov 25;244(22):6049-55. PMID:5389100</ref>
2HH0 is a prion protein that manifests in bovine(cattle) and can lead to degenerative central nervous system tissues. The word “prion” is derived from “protein + infection.”  Prions were discovered in 1997 by Stanley B. Prusiner of the University of California.(1) They are infected proteins and may lay dormant for many years before they activate and cause damage to the brain and spinal cord. <ref name="Luginbuhl, B.">Luginbuhl, B., Kanyo, Z., Jones, R.M., Fletterick, R.J., Prusiner, S.B., Cohen, F.E., Williamson, R.A., Burton, D.R., & Pluckthun, A. Directed evolution of an anti-prion protein scFv fragment to an affinity of 1 pM and its structural interpretation. 2006. J.Mol.Biol. 2006 363:75-97.</ref>




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