2jhc: Difference between revisions
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[[Image:2jhc.gif|left|200px]]<br /><applet load="2jhc" size=" | [[Image:2jhc.gif|left|200px]]<br /><applet load="2jhc" size="350" color="white" frame="true" align="right" spinBox="true" | ||
caption="2jhc, resolution 3.00Å" /> | caption="2jhc, resolution 3.00Å" /> | ||
'''THE STRUCTURE OF BLUETONGUE VIRUS VP4 REVEALS A MULTIFUNCTIONAL RNA-CAPPING PRODUCTION-LINE'''<br /> | '''THE STRUCTURE OF BLUETONGUE VIRUS VP4 REVEALS A MULTIFUNCTIONAL RNA-CAPPING PRODUCTION-LINE'''<br /> | ||
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==About this Structure== | ==About this Structure== | ||
2JHC is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bluetongue_virus_10_(isolate_usa) Bluetongue virus 10 (isolate usa)] with GUN as [http://en.wikipedia.org/wiki/ligand ligand]. Known structural/functional Site: <scene name='pdbsite=AC1:Gun Binding Site For Chain A'>AC1</scene>. Full crystallographic information is available from [http:// | 2JHC is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bluetongue_virus_10_(isolate_usa) Bluetongue virus 10 (isolate usa)] with <scene name='pdbligand=GUN:'>GUN</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Known structural/functional Site: <scene name='pdbsite=AC1:Gun Binding Site For Chain A'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JHC OCA]. | ||
==Reference== | ==Reference== | ||
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[[Category: virion protein]] | [[Category: virion protein]] | ||
''Page seeded by [http:// | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 23 14:53:06 2008'' | ||
Revision as of 15:53, 23 January 2008
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THE STRUCTURE OF BLUETONGUE VIRUS VP4 REVEALS A MULTIFUNCTIONAL RNA-CAPPING PRODUCTION-LINE
OverviewOverview
Eukaryotic organisms cap the 5' ends of their messenger RNAs by a series, of four chemical reactions. Some viruses achieve this using a single, molecule; the crystal structure of such an enzyme from bluetongue virus, reveals an elongated modular architecture that provides a scaffold for an, assemblage of active sites, two contributed by a domain of novel, structure.
About this StructureAbout this Structure
2JHC is a Single protein structure of sequence from Bluetongue virus 10 (isolate usa) with as ligand. Known structural/functional Site: . Full crystallographic information is available from OCA.
ReferenceReference
Bluetongue virus VP4 is an RNA-capping assembly line., Sutton G, Grimes JM, Stuart DI, Roy P, Nat Struct Mol Biol. 2007 May;14(5):449-51. Epub 2007 Apr 8. PMID:17417654
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