2hsg: Difference between revisions
New page: left|200px<br /><applet load="2hsg" size="450" color="white" frame="true" align="right" spinBox="true" caption="2hsg, resolution 2.500Å" /> '''Structure of transc... |
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[[Image:2hsg.jpg|left|200px]]<br /><applet load="2hsg" size=" | [[Image:2hsg.jpg|left|200px]]<br /><applet load="2hsg" size="350" color="white" frame="true" align="right" spinBox="true" | ||
caption="2hsg, resolution 2.500Å" /> | caption="2hsg, resolution 2.500Å" /> | ||
'''Structure of transcription regulator CcpA in its DNA-free state'''<br /> | '''Structure of transcription regulator CcpA in its DNA-free state'''<br /> | ||
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==About this Structure== | ==About this Structure== | ||
2HSG is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_megaterium Bacillus megaterium]. Full crystallographic information is available from [http:// | 2HSG is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_megaterium Bacillus megaterium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HSG OCA]. | ||
==Reference== | ==Reference== | ||
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[[Category: transcriptional regulator]] | [[Category: transcriptional regulator]] | ||
''Page seeded by [http:// | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 23 14:52:47 2008'' | ||
Revision as of 15:52, 23 January 2008
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Structure of transcription regulator CcpA in its DNA-free state
OverviewOverview
The catabolite control protein A (CcpA) from Bacillus megaterium is a, member of the bacterial repressor protein family GalR-LacI. CcpA functions, as master transcriptional regulator of carbon catabolite, repression/regulation in firmicutes. Here we present the crystal structure, of full-length apo CcpA at 2.5 A resolution from B. megaterium. The, structure reveals the location of the helix-turn-helix domain as well as, the hinge region, which were not visible due to their high flexibility in, earlier crystallographic studies on CcpA molecules. The structure of the, apo CcpA homodimer in the present form is in contrast to other reported, structures for CcpA.
About this StructureAbout this Structure
2HSG is a Single protein structure of sequence from Bacillus megaterium. Full crystallographic information is available from OCA.
ReferenceReference
Structure of full-length transcription regulator CcpA in the apo form., Loll B, Saenger W, Biesiadka J, Biochim Biophys Acta. 2007 Apr 18;. PMID:17500051
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