2vx0: Difference between revisions

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{{Seed}}
[[Image:2vx0.png|left|200px]]
[[Image:2vx0.png|left|200px]]


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{{ABSTRACT_PUBMED_18434142}}
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==About this Structure==
==About this Structure==
2VX0 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VX0 OCA].  
[[2vx0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VX0 OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:18434142</ref><references group="xtra"/>
<ref group="xtra">PMID:18851911</ref><ref group="xtra">PMID:18434142</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Receptor protein-tyrosine kinase]]
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[[Category: Tyrosine-protein kinase]]
[[Category: Tyrosine-protein kinase]]
[[Category: Unphosphorylated]]
[[Category: Unphosphorylated]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 23:56:58 2009''

Revision as of 03:10, 15 March 2011

File:2vx0.png

Template:STRUCTURE 2vx0

EPHB4 KINASE DOMAIN INHIBITOR COMPLEXEPHB4 KINASE DOMAIN INHIBITOR COMPLEX

Template:ABSTRACT PUBMED 18851911

About this StructureAbout this Structure

2vx0 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1][xtra 2]

  1. Bardelle C, Coleman T, Cross D, Davenport S, Kettle JG, Ko EJ, Leach AG, Mortlock A, Read J, Roberts NJ, Robins P, Williams EJ. Inhibitors of the tyrosine kinase EphB4. Part 2: structure-based discovery and optimisation of 3,5-bis substituted anilinopyrimidines. Bioorg Med Chem Lett. 2008 Nov 1;18(21):5717-21. Epub 2008 Sep 27. PMID:18851911 doi:10.1016/j.bmcl.2008.09.087
  2. Bardelle C, Cross D, Davenport S, Kettle JG, Ko EJ, Leach AG, Mortlock A, Read J, Roberts NJ, Robins P, Williams EJ. Inhibitors of the tyrosine kinase EphB4. Part 1: Structure-based design and optimization of a series of 2,4-bis-anilinopyrimidines. Bioorg Med Chem Lett. 2008 May 1;18(9):2776-80. Epub 2008 Apr 10. PMID:18434142 doi:10.1016/j.bmcl.2008.04.015

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