2x0v: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
[[Image:2x0v.png|left|200px]] | [[Image:2x0v.png|left|200px]] | ||
| Line 20: | Line 19: | ||
==About this Structure== | ==About this Structure== | ||
[[2x0v]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X0V OCA]. | |||
==Reference== | ==Reference== | ||
| Line 41: | Line 40: | ||
[[Category: Transcription regulation]] | [[Category: Transcription regulation]] | ||
[[Category: Tumor suppressor]] | [[Category: Tumor suppressor]] | ||
Revision as of 01:15, 15 March 2011
STRUCTURE OF THE P53 CORE DOMAIN MUTANT Y220C BOUND TO 4-(TRIFLUOROMETHYL)BENZENE-1,2-DIAMINESTRUCTURE OF THE P53 CORE DOMAIN MUTANT Y220C BOUND TO 4-(TRIFLUOROMETHYL)BENZENE-1,2-DIAMINE
Template:ABSTRACT PUBMED 20142040
About this StructureAbout this Structure
2x0v is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Basse N, Kaar JL, Settanni G, Joerger AC, Rutherford TJ, Fersht AR. Toward the rational design of p53-stabilizing drugs: probing the surface of the oncogenic Y220C mutant. Chem Biol. 2010 Jan 29;17(1):46-56. PMID:20142040 doi:10.1016/j.chembiol.2009.12.011
- ↑ Joerger AC, Ang HC, Fersht AR. Structural basis for understanding oncogenic p53 mutations and designing rescue drugs. Proc Natl Acad Sci U S A. 2006 Oct 10;103(41):15056-61. Epub 2006 Oct 2. PMID:17015838