2x1n: Difference between revisions
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Revision as of 01:06, 15 March 2011
TRUNCATION AND OPTIMISATION OF PEPTIDE INHIBITORS OF CDK2, CYCLIN A THROUGH STRUCTURE GUIDED DESIGNTRUNCATION AND OPTIMISATION OF PEPTIDE INHIBITORS OF CDK2, CYCLIN A THROUGH STRUCTURE GUIDED DESIGN
Template:ABSTRACT PUBMED 20146435
About this StructureAbout this Structure
2x1n is a 5 chain structure of Cell Division Protein Kinase 2 with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 2wha. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ McIntyre NA, McInnes C, Griffiths G, Barnett AL, Kontopidis G, Slawin AM, Jackson W, Thomas M, Zheleva DI, Wang S, Blake DG, Westwood NJ, Fischer PM. Design, synthesis, and evaluation of 2-methyl- and 2-amino-N-aryl-4,5-dihydrothiazolo[4,5-h]quinazolin-8-amines as ring-constrained 2-anilino-4-(thiazol-5-yl)pyrimidine cyclin-dependent kinase inhibitors. J Med Chem. 2010 Mar 11;53(5):2136-45. PMID:20146435 doi:10.1021/jm901660c
- ↑ Kontopidis G, Andrews MJ, McInnes C, Plater A, Innes L, Renachowski S, Cowan A, Fischer PM. Truncation and Optimisation of Peptide Inhibitors of Cyclin-Dependent Kinase 2-Cyclin A Through Structure-Guided Design. ChemMedChem. 2009 May 26. PMID:19472269 doi:10.1002/cmdc.200900093
Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)
OCACategories:
- Pages with broken file links
- Homo sapiens
- Non-specific serine/threonine protein kinase
- Andrews, M J.
- Barnett, A L.
- Blake, D G.
- Cowan, A.
- Fischer, P M.
- Griffiths, G.
- Innes, L.
- Jackson, W.
- Kontopidis, G.
- Mcinnes, C.
- Mcintyre, N A.
- Plater, A.
- Renachowski, S.
- Slawin, A M.Z.
- Thomas, M.
- Wang, S.
- Westwood, N J.
- Zheleva, D I.
- Cell cycle
- Cell division
- Inhibition
- Serine/threonine-protein kinase
- Transferase