2fx9: Difference between revisions
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Revision as of 00:21, 15 March 2011
Crystal structure of hiv-1 neutralizing human fab 4e10 in complex with a thioether-linked peptide encompassing the 4e10 epitope on gp41Crystal structure of hiv-1 neutralizing human fab 4e10 in complex with a thioether-linked peptide encompassing the 4e10 epitope on gp41
Template:ABSTRACT PUBMED 17125793
About this StructureAbout this Structure
2fx9 is a 6 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Cardoso RM, Brunel FM, Ferguson S, Zwick M, Burton DR, Dawson PE, Wilson IA. Structural basis of enhanced binding of extended and helically constrained peptide epitopes of the broadly neutralizing HIV-1 antibody 4E10. J Mol Biol. 2007 Feb 2;365(5):1533-44. Epub 2006 Nov 10. PMID:17125793 doi:10.1016/j.jmb.2006.10.088
- ↑ Cardoso RM, Zwick MB, Stanfield RL, Kunert R, Binley JM, Katinger H, Burton DR, Wilson IA. Broadly neutralizing anti-HIV antibody 4E10 recognizes a helical conformation of a highly conserved fusion-associated motif in gp41. Immunity. 2005 Feb;22(2):163-73. PMID:15723805 doi:10.1016/j.immuni.2004.12.011