TolA: Difference between revisions

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==Structure==
==Structure==
TolA comprises of three domains: domain I, from residues 1-47 including a 20-residue hydrophobic membrane spanning region; domain II, from residues 48-301, which forms a rigid helix connecting the domains either side of it; and domain III from residues 302-421, which may be involved in the function of TolA by interacting with the periplasmic or outer membrane proteins, due to the tethering to domain II.<ref name='Sharyn'>PMID: 8416897</ref>
TolA comprises of three domains: domain I, from residues 1-47 including a 20-residue hydrophobic membrane spanning region; domain II, from residues 48-301, which forms a rigid helix connecting the domains either side of it; and domain III (see [[TolA C-Termainal Domain]]) from residues 302-421, which may be involved in the function of TolA by interacting with the periplasmic or outer membrane proteins, due to the tethering to domain II.<ref name='Sharyn'>PMID: 8416897</ref>


==Function==
==Function==

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Laura McCauley, Michal Harel