Colicin Ia: Difference between revisions
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==Mechanism of uptake== | ==Mechanism of uptake== | ||
{{STRUCTURE_2hdi | PDB=2hdi | SCENE= }} | |||
The N terminus is responsible for the translocation of colicin Ia across the membrane of the targeted cell. There is much flexibility on this region<ref> PMID: 15452437 </ref> | The N terminus is responsible for the translocation of colicin Ia across the membrane of the targeted cell. There is much flexibility on this region<ref> PMID: 15452437 </ref>. | ||
The structure shows the receptor binding domain of ColIa bound to its outer membrane receptor, Cir. | |||
==Killing Activities== | ==Killing Activities== | ||
Revision as of 16:20, 11 February 2011
Colicin Ia is a type of Colicin, a bacteriocin made by E. coli which acts against other nearby E. coli to kill them by forming a pore in the membrane, leading to depolarisation of the membrane which kills the cell.
Synthesis and releaseSynthesis and release
Mechanism of uptakeMechanism of uptake
Template:STRUCTURE 2hdi The N terminus is responsible for the translocation of colicin Ia across the membrane of the targeted cell. There is much flexibility on this region[1]. The structure shows the receptor binding domain of ColIa bound to its outer membrane receptor, Cir.