User:Wayne Decatur/Homology Modeling: Difference between revisions

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*[http://zhanglab.ccmb.med.umich.edu/I-TASSER/ I-Tasser]:

** '''Employs more of comparative protein modelling based on protein threading and not a homology model from what I gather '''

**"I-Tasser is an Internet service for protein structure and function predictions. 3D models are built based on multiple-threading alignments by LOMETS and iterative TASSER simulations; function ~~inslights~~ are then derived by matching the predicted models with protein function databases. I-TASSER (as 'Zhang-Server') was ranked as the No 1 server for protein structure prediction in recent CASP7 and CASP8 experiments. The server is in active development with the goal to provide the most accurate structural and function predictions using state-of-the-art algorithms."

**"I-Tasser is an Internet service for protein structure and function predictions. 3D models are built based on multiple-threading alignments by LOMETS and iterative TASSER simulations; function insights are then derived by matching the predicted models with protein function databases. I-TASSER (as 'Zhang-Server') was ranked as the No 1 server for protein structure prediction in recent CASP7 and CASP8 experiments. The server is in active development with the goal to provide the most accurate structural and function predictions using state-of-the-art algorithms."

**[http://www.biotechniques.com/news/biotechniquesNews/biotechniques-309517.html?utm_source=BioTechniques+Newsletters+%2526+e-Alerts&utm_campaign=7a92dd2401-Methods+Newsletter&utm_medium=email Feb. 2011 Biotechniques article about the P.I. behind this server, Yang Zhang].

*[http://swift.cmbi.ru.nl/teach/courses/index.html Course on Homology Modeling]

*[http://www.udel.edu/chem/bahnson/chem645/Part-I-645homology_F08.html Class on Homology Modeling]

@@ Line 15: / Line 15: @@
 *[http://zhanglab.ccmb.med.umich.edu/I-TASSER/ I-Tasser]:
 ** '''Employs more of comparative protein modelling based on protein threading and not a homology model from what I gather '''
-**"I-Tasser is an Internet service for protein structure and function predictions. 3D models are built based on multiple-threading alignments by LOMETS and iterative TASSER simulations; function inslights are then derived by matching the predicted models with protein function databases. I-TASSER (as 'Zhang-Server') was ranked as the No 1 server for protein structure prediction in recent CASP7 and CASP8 experiments. The server is in active development with the goal to provide the most accurate structural and function predictions using state-of-the-art algorithms."
+**"I-Tasser is an Internet service for protein structure and function predictions. 3D models are built based on multiple-threading alignments by LOMETS and iterative TASSER simulations; function insights are then derived by matching the predicted models with protein function databases. I-TASSER (as 'Zhang-Server') was ranked as the No 1 server for protein structure prediction in recent CASP7 and CASP8 experiments. The server is in active development with the goal to provide the most accurate structural and function predictions using state-of-the-art algorithms."
+**[http://www.biotechniques.com/news/biotechniquesNews/biotechniques-309517.html?utm_source=BioTechniques+Newsletters+%2526+e-Alerts&utm_campaign=7a92dd2401-Methods+Newsletter&utm_medium=email Feb. 2011 Biotechniques article about the P.I. behind this server, Yang Zhang].
 *[http://swift.cmbi.ru.nl/teach/courses/index.html Course on Homology Modeling]
 *[http://www.udel.edu/chem/bahnson/chem645/Part-I-645homology_F08.html Class on Homology Modeling]