3hp5: Difference between revisions
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Revision as of 08:23, 12 January 2011
Crystal Structure of Human p38alpha complexed with a pyrimidopyridazinone compoundCrystal Structure of Human p38alpha complexed with a pyrimidopyridazinone compound
Template:ABSTRACT PUBMED 19751974
About this StructureAbout this Structure
3hp5 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Selness SR, Devraj RV, Monahan JB, Boehm TL, Walker JK, Devadas B, Durley RC, Kurumbail R, Shieh H, Xing L, Hepperle M, Rucker PV, Jerome KD, Benson AG, Marrufo LD, Madsen HM, Hitchcock J, Owen TJ, Christie L, Promo MA, Hickory BS, Alvira E, Naing W, Blevis-Bal R. Discovery of N-substituted pyridinones as potent and selective inhibitors of p38 kinase. Bioorg Med Chem Lett. 2009 Oct 15;19(20):5851-6. Epub 2009 Aug 27. PMID:19751974 doi:10.1016/j.bmcl.2009.08.082