3pd8: Difference between revisions
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{{STRUCTURE_3pd8| PDB=3pd8 | SCENE= }} | |||
===X-ray structure of the ligand-binding core of GluA2 in complex with (S)-7-HPCA at 2.5 A resolution=== | |||
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{{ABSTRACT_PUBMED_21067182}} | |||
==About this Structure== | |||
[[3pd8]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PD8 OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:21067182</ref><ref group="xtra">PMID:12215417</ref><ref group="xtra">PMID:11086992</ref><references group="xtra"/> | |||
[[Category: Rattus norvegicus]] | |||
[[Category: Frydenvang, K.]] | |||
[[Category: Kastrup, J S.]] | |||
[[Category: Agonist complex]] | |||
[[Category: Ionotropic glutamate receptor glua2]] | |||
[[Category: Ligand-binding core]] | |||
[[Category: Membrane protein]] | |||
Revision as of 21:40, 29 December 2010
X-ray structure of the ligand-binding core of GluA2 in complex with (S)-7-HPCA at 2.5 A resolutionX-ray structure of the ligand-binding core of GluA2 in complex with (S)-7-HPCA at 2.5 A resolution
Template:ABSTRACT PUBMED 21067182
About this StructureAbout this Structure
3pd8 is a 3 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Frydenvang K, Pickering DS, Greenwood JR, Krogsgaard-Larsen N, Brehm L, Nielsen B, Vogensen SB, Hald H, Kastrup JS, Krogsgaard-Larsen P, Clausen RP. Biostructural and Pharmacological Studies of Bicyclic Analogues of the 3-Isoxazolol Glutamate Receptor Agonist Ibotenic Acid. J Med Chem. 2010 Nov 10. PMID:21067182 doi:10.1021/jm101218a
- ↑ Hogner A, Kastrup JS, Jin R, Liljefors T, Mayer ML, Egebjerg J, Larsen IK, Gouaux E. Structural basis for AMPA receptor activation and ligand selectivity: crystal structures of five agonist complexes with the GluR2 ligand-binding core. J Mol Biol. 2002 Sep 6;322(1):93-109. PMID:12215417
- ↑ Armstrong N, Gouaux E. Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structures of the GluR2 ligand binding core. Neuron. 2000 Oct;28(1):165-81. PMID:11086992