1kpc: Difference between revisions
New page: left|200px<br /> <applet load="1kpc" size="450" color="white" frame="true" align="right" spinBox="true" caption="1kpc, resolution 2.2Å" /> '''PKCI-1-APO+ZINC'''<b... |
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==About this Structure== | ==About this Structure== | ||
1KPC is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1KPC OCA]]. | 1KPC is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]]. Structure known Active Sites: ZNA, ZNB, ZNC and ZND. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1KPC OCA]]. | ||
==Reference== | ==Reference== | ||
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[[Category: zinc binding protein]] | [[Category: zinc binding protein]] | ||
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Revision as of 12:11, 30 October 2007
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PKCI-1-APO+ZINC
OverviewOverview
The three-dimensional structure of protein kinase C interacting protein 1, (PKCI-1) has been solved to high resolution by x-ray crystallography using, single isomorphous replacement with anomalous scattering. The gene, encoding human PKCI-1 was cloned from a cDNA library by using a partial, sequence obtained from interactions identified in the yeast two-hybrid, system between PKCI-1 and the regulatory domain of protein kinase C-beta., The PKCI-1 protein was expressed in Pichia pastoris as a dimer of two, 13.7-kDa polypeptides. PKCI-1 is a member of the HIT family of proteins, shown by sequence identity to be conserved in a broad range of organisms, including mycoplasma, plants, and humans. Despite the ubiquity of this, protein sequence in nature, no distinct function has been shown for ... [(full description)]
About this StructureAbout this Structure
1KPC is a [Single protein] structure of sequence from [Homo sapiens]. Structure known Active Sites: ZNA, ZNB, ZNC and ZND. Full crystallographic information is available from [OCA].
ReferenceReference
Three-dimensional structure of human protein kinase C interacting protein 1, a member of the HIT family of proteins., Lima CD, Klein MG, Weinstein IB, Hendrickson WA, Proc Natl Acad Sci U S A. 1996 May 28;93(11):5357-62. PMID:8643579
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