Molecular Playground/Taxol: Difference between revisions
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Docetaxel (Taxotere, sanofi-aventis) is a semi-synthetic analog of Taxol that was discovered during the search for a more easily produced taxane anti-cancer agent. The hydroxyl group modification on docetaxel leads to an increase in the lipid solubility of the drug. It was first approved by the FDA in 1996 and is currently used in the treatment of breast, stomach and prostate cancer. | Docetaxel (Taxotere, sanofi-aventis) is a semi-synthetic analog of Taxol that was discovered during the search for a more easily produced taxane anti-cancer agent. The hydroxyl group modification on docetaxel leads to an increase in the lipid solubility of the drug. It was first approved by the FDA in 1996 and is currently used in the treatment of breast, stomach and prostate cancer. | ||
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caption='Paclitaxel (also known as Taxol)' /> <scene name='Rohan_Patil/Sandbox1/Taxol/6'>Paclitaxel</scene> | caption='Paclitaxel (also known as Taxol)' /> <scene name='Rohan_Patil/Sandbox1/Taxol/6'>Paclitaxel</scene> | ||