1guo: Difference between revisions
New page: left|200px<br /> <applet load="1guo" size="450" color="white" frame="true" align="right" spinBox="true" caption="1guo, resolution 2.50Å" /> '''MOPII FROM CLOSTRID... |
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==About this Structure== | ==About this Structure== | ||
1GUO is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Clostridium_pasteurianum Clostridium pasteurianum]] with MOO as [[http://en.wikipedia.org/wiki/ligand ligand]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1GUO OCA]]. | 1GUO is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Clostridium_pasteurianum Clostridium pasteurianum]] with MOO as [[http://en.wikipedia.org/wiki/ligand ligand]]. Structure known Active Site: T11. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1GUO OCA]]. | ||
==Reference== | ==Reference== | ||
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[[Category: multigene fam]] | [[Category: multigene fam]] | ||
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Revision as of 12:10, 30 October 2007
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MOPII FROM CLOSTRIDIUM PASTEURIANUM COMPLEXED WITH MOLYBDATE
OverviewOverview
MopII from Clostridium pasteurianum is a molbindin family member. These, proteins may serve as intracellular storage facilities for molybdate, which they bind with high specificity. High resolution structures of MopII, in a number of states, including the first structure of an apo-molbindin, together with calorimetric data, allow us to describe ligand binding and, provide support for the proposed storage function of the protein. MopII, assembles as a trimer of dimers and binds eight oxyanions at two types of, binding sites located at intersubunit interfaces. Two type 1 sites are on, the molecular 3-fold axis and three pairs of type 2 sites occur on the, molecular 2-fold axes. The hexamer is largely unaffected by the binding of, ligand. Molybdate is admitted to the otherwise inaccessible ... [(full description)]
About this StructureAbout this Structure
1GUO is a [Single protein] structure of sequence from [Clostridium pasteurianum] with MOO as [ligand]. Structure known Active Site: T11. Full crystallographic information is available from [OCA].
ReferenceReference
Passive acquisition of ligand by the MopII molbindin from Clostridium pasteurianum: structures of apo and oxyanion-bound forms., Schuttelkopf AW, Harrison JA, Boxer DH, Hunter WN, J Biol Chem. 2002 Apr 26;277(17):15013-20. Epub 2002 Feb 8. PMID:11836258
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