1gug: Difference between revisions
New page: left|200px<br /> <applet load="1gug" size="450" color="white" frame="true" align="right" spinBox="true" caption="1gug, resolution 1.60Å" /> '''MOPII FROM CLOSTRID... |
No edit summary |
||
| Line 8: | Line 8: | ||
==About this Structure== | ==About this Structure== | ||
1GUG is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Clostridium_pasteurianum Clostridium pasteurianum]] with WO4, CL and NA as [[http://en.wikipedia.org/wiki/ligands ligands]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1GUG OCA]]. | 1GUG is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Clostridium_pasteurianum Clostridium pasteurianum]] with WO4, CL and NA as [[http://en.wikipedia.org/wiki/ligands ligands]]. Structure known Active Site: T11. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1GUG OCA]]. | ||
==Reference== | ==Reference== | ||
| Line 24: | Line 24: | ||
[[Category: mop]] | [[Category: mop]] | ||
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 11:15:02 2007'' | ||
Revision as of 12:10, 30 October 2007
|
MOPII FROM CLOSTRIDIUM PASTEURIANUM COMPLEXED WITH TUNGSTATE
OverviewOverview
MopII from Clostridium pasteurianum is a molbindin family member. These, proteins may serve as intracellular storage facilities for molybdate, which they bind with high specificity. High resolution structures of MopII, in a number of states, including the first structure of an apo-molbindin, together with calorimetric data, allow us to describe ligand binding and, provide support for the proposed storage function of the protein. MopII, assembles as a trimer of dimers and binds eight oxyanions at two types of, binding sites located at intersubunit interfaces. Two type 1 sites are on, the molecular 3-fold axis and three pairs of type 2 sites occur on the, molecular 2-fold axes. The hexamer is largely unaffected by the binding of, ligand. Molybdate is admitted to the otherwise inaccessible ... [(full description)]
About this StructureAbout this Structure
1GUG is a [Single protein] structure of sequence from [Clostridium pasteurianum] with WO4, CL and NA as [ligands]. Structure known Active Site: T11. Full crystallographic information is available from [OCA].
ReferenceReference
Passive acquisition of ligand by the MopII molbindin from Clostridium pasteurianum: structures of apo and oxyanion-bound forms., Schuttelkopf AW, Harrison JA, Boxer DH, Hunter WN, J Biol Chem. 2002 Apr 26;277(17):15013-20. Epub 2002 Feb 8. PMID:11836258
Page seeded by OCA on Tue Oct 30 11:15:02 2007