1gue: Difference between revisions
New page: left|200px<br /> <applet load="1gue" size="450" color="white" frame="true" align="right" spinBox="true" caption="1gue, resolution 2.27Å" /> '''SENSORY RHODOPSIN I... |
No edit summary |
||
| Line 8: | Line 8: | ||
==About this Structure== | ==About this Structure== | ||
1GUE is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Natronomonas_pharaonis Natronomonas pharaonis]] with CL and RET as [[http://en.wikipedia.org/wiki/ligands ligands]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1GUE OCA]]. | 1GUE is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Natronomonas_pharaonis Natronomonas pharaonis]] with CL and RET as [[http://en.wikipedia.org/wiki/ligands ligands]]. Structure known Active Site: RET. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1GUE OCA]]. | ||
==Reference== | ==Reference== | ||
| Line 28: | Line 28: | ||
[[Category: phototaxis]] | [[Category: phototaxis]] | ||
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 11:14:48 2007'' | ||
Revision as of 12:10, 30 October 2007
|
SENSORY RHODOPSIN II
OverviewOverview
Sensory rhodopsins are the primary receptors of vision in animals and, phototaxis in microorganisms. Light triggers the rapid isomerization of a, buried retinal chromophore, which the protein both accommodates and, amplifies into the larger structural rearrangements required for, signaling. We trapped an early intermediate of the photocycle of sensory, rhodopsin II from Natronobacterium pharaonis (pSRII) in 3D crystals and, determined its X-ray structure to 2.3 A resolution. The observed, structural rearrangements were localized near the retinal chromophore, with a key water molecule becoming disordered and the retinal's, beta-ionone ring undergoing a prominent movement. Comparison with the, early structural rearrangements of bacteriorhodopsin illustrates how, modifications in the retinal ... [(full description)]
About this StructureAbout this Structure
1GUE is a [Single protein] structure of sequence from [Natronomonas pharaonis] with CL and RET as [ligands]. Structure known Active Site: RET. Full crystallographic information is available from [OCA].
ReferenceReference
Early structural rearrangements in the photocycle of an integral membrane sensory receptor., Edman K, Royant A, Nollert P, Maxwell CA, Pebay-Peyroula E, Navarro J, Neutze R, Landau EM, Structure. 2002 Apr;10(4):473-82. PMID:11937052
Page seeded by OCA on Tue Oct 30 11:14:48 2007