P53R2: Difference between revisions
No edit summary |
No edit summary |
||
| Line 4: | Line 4: | ||
[[Image:3hf1.png|left|200px]] | [[Image:3hf1.png|left|200px]] | ||
[[p53R2]] is an oxydoreductase composed of 351 residues. It is a small subunit of the ribonucleotide reductase (RNR). | [[p53R2]] is an oxydoreductase composed of 351 residues, that could be a new target for an anticancer therapy. It is a small subunit of the ribonucleotide reductase (RNR). | ||
RNR catalyses the reduction of the four nucleotides to desoxyribonucleotides. It exists three classes of RNR. Class I RNR is a tetramer composed of the two types of subunits with stoichiometry α2β2 and three subunits have been identified in mammals : | RNR catalyses the reduction of the four nucleotides to desoxyribonucleotides. It exists three classes of RNR. Class I RNR is a tetramer composed of the two types of subunits with stoichiometry α2β2 and three subunits have been identified in mammals : | ||