AZT-resistant HIV-1 reverse transcriptase: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
==Role of Reverse Transcriptase in HIV Replication== | ==Role of Reverse Transcriptase in HIV Replication== | ||
Reverse Transcriptase (RT) allows HIV to create DNA from its RNA. | Reverse Transcriptase (RT) allows HIV to create DNA from its RNA. RT has two enzymatic activities: DNA polymerase and RNase H. DNA polymerase is necessary for copying a DNA or RNA template, while RNase H cleaves the RNA that is part of the DNA/RNA duplex. These two activities combine to convert RNA into linear, double-stranded DNA. This DNA is then incorporated in the host's genome. | ||
Revision as of 05:49, 4 November 2010
Role of Reverse Transcriptase in HIV ReplicationRole of Reverse Transcriptase in HIV Replication
Reverse Transcriptase (RT) allows HIV to create DNA from its RNA. RT has two enzymatic activities: DNA polymerase and RNase H. DNA polymerase is necessary for copying a DNA or RNA template, while RNase H cleaves the RNA that is part of the DNA/RNA duplex. These two activities combine to convert RNA into linear, double-stranded DNA. This DNA is then incorporated in the host's genome.
AZT ResistanceAZT Resistance