Bungarotoxin: Difference between revisions
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New page: left|200px|thumb|Crystal Structure of α-Bungarotoxin [[2abx]] {{STRUCTURE_2abx| PDB=2abx | SIZE=300| SCENE= |right|CAPTION=α-Bungarotoxin 2abx }} |
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[[Image:2abx.png|left|200px|thumb|Crystal Structure of α-Bungarotoxin [[2abx]]]] | [[Image:2abx.png|left|200px|thumb|Crystal Structure of α-Bungarotoxin [[2abx]]]] | ||
{{STRUCTURE_2abx| PDB=2abx | SIZE=300| SCENE= |right|CAPTION=α-Bungarotoxin [[2abx]] }} | {{STRUCTURE_2abx| PDB=2abx | SIZE=300| SCENE=Bungarotoxin/Cv/1 |right|CAPTION=α-Bungarotoxin [[2abx]] }} | ||
[[Bungarotoxin|Bungarotoxins]]. α-Bungarotoxin (α-BGT), β-Bungarotoxin (β-BGT), γ-Bungarotoxin (γ-BGT) and κ-Bungarotoxin (κ-BGT) are snake toxins from banded krait. α-BGT binds irreversibly to the acetylcholine receptor (AChR) causing paralysis and death. β-BGT binds to the presynaptic terminal causing release of acetylcholine. The images at the left and at the right correspond to one representative Bungarotoxin , ''i.e.'' the crystal structure of α-Bungarotoxin ([[2abx]]). | |||
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== 3D Structures of Thermolysin == | |||
=== Bungarotoxin === | |||
[[2abx]] – α-BGT <br /> | |||
[[1kfh]], [[1ik8]], [[1ikc]], [[1idi]], [[1idl]], [[2nbt]] – α-BGT - NMR<br /> | |||
[[1mr6]] – γ-BGT – NMR<br /> | |||
[[1kba]] – κ-BGT<br /> | |||
=== BGT+binding peptide === | |||
[[1rji]], [[1l4w]], [[1ljz]], [[1kc4]], [[1kl8]], [[1hc9]], [[1jbd]], [[1haa]], [[1haj]], [[1idg]], [[1idh]], [[1hoy]], [[1bxp]], [[1btx]], [[1abt]] – α-BGT+AChR peptide - NMR<br /> | |||
== BGT+ AChR subunit == | |||
[[2qc1]] – α-BGT+mAChR a subunit <br /> | |||
Revision as of 11:42, 21 October 2010
Bungarotoxins. α-Bungarotoxin (α-BGT), β-Bungarotoxin (β-BGT), γ-Bungarotoxin (γ-BGT) and κ-Bungarotoxin (κ-BGT) are snake toxins from banded krait. α-BGT binds irreversibly to the acetylcholine receptor (AChR) causing paralysis and death. β-BGT binds to the presynaptic terminal causing release of acetylcholine. The images at the left and at the right correspond to one representative Bungarotoxin , i.e. the crystal structure of α-Bungarotoxin (2abx).
3D Structures of Thermolysin3D Structures of Thermolysin
BungarotoxinBungarotoxin
2abx – α-BGT
1kfh, 1ik8, 1ikc, 1idi, 1idl, 2nbt – α-BGT - NMR
1mr6 – γ-BGT – NMR
1kba – κ-BGT
BGT+binding peptideBGT+binding peptide
1rji, 1l4w, 1ljz, 1kc4, 1kl8, 1hc9, 1jbd, 1haa, 1haj, 1idg, 1idh, 1hoy, 1bxp, 1btx, 1abt – α-BGT+AChR peptide - NMR
BGT+ AChR subunitBGT+ AChR subunit
2qc1 – α-BGT+mAChR a subunit