Pharmaceutical Drug Targets and Diseases: Difference between revisions

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**Cancer
**Cancer
***[[Antizyme Inhibitor]]
*** See: [[Cancer]]
***Caspases
****[[Molecular_Playground/Caspase-6|Caspase-6]]
****[[Molecular_Playground/Caspase-7_Dynamics|Caspase-7 Dynamics]]
****[[Molecular_Playground/Caspase-9_Regulation|Caspase-9 Regulation]]
***[[User:Greg_Black/Sandbox_1|Cisplatin Information]]
***[[Michael Purol Sandbox 1|Cyclin Dependent Kinase Inhibitor]]
***[[NADPH Cytochrome P450 Oxidoreductase|Cytochrome P450 Oxidoreductase]]
***[[6-deoxyerythronolide_B_synthase_%28DEBS%29|DEBS]]
***[[Dihydrofolate_reductase|Dihydrofolate Reductase, the Target of Methotrexate]]
***[[Farnesoid X Receptor]]
***Growth Factors & Receptors
****Epidermal Growth Factor
*****[[Epidermal Growth Factor]]
*****[[Epidermal Growth Factor Receptor]]
****[[Hepatocyte Growth Factor Receptor]]
****[[Human Epidermal Growth Factor Receptor 2]]
****Insulin-Like Growth Factor
*****[[Insulin-Like Growth Factor-1]]
*****[[Insulin-Like Growth Factor-1 Receptor]]
****Vascular Growth Factor
*****[[Vascular Endothelial Growth Factor]]
*****[[Vascular Endothelial Growth Factor Receptor]]
***[[Molecular_Playground/FIH|Hypoxia Inducible Factor (HIF)]]
***[[User:Yash_Patankar/Sandbox_1|Heat Shock Protein 90]]
***[[1ebm|Human 8-Oxoguanine Glycosylase Structure and Mechanism (HOGG1)]]
***Kinases
****[[Cory_Tiedeman_sandbox|Cyclin Dependent Kinase-4]]
****[[Cell Division Cycle 7-Related Protein Kinase]]
****[[Mammalian Target of Rapamycin]]
****Mitogen-Activated Proteins
*****Mitogen-Activated Protein Kinase
*****Mitogen-Activated Protein Kinase Kinase
*****Mitogen-Activated Protein Kinase Kinase Kinase
******[[c-Raf]]
****[[Phosphatidylinositol 3-Kinase]]
****[[SRC]]
***[[P-glycoprotein:_Why_Cancer_Drugs_Fail|P-Glycoprotein: Why Cancer Drugs Fail]]
***Oncogenes
****[[C-Myc]] - Proto-Oncogenic Gene
****[[P53]] - Tumor Suppressing Gene
****[[PTEN]]
****[[Matt Routh sandbox|MDM2 Bound to p53]]
****[[SRC]] - Proto-Oncogenic Tyrosine Kinase Gene
***[[Ann_Taylor_sandbox_Proteins_in_Cancer|Proteins in Cancer]]
***[[Ras|Ras Superfamily]]
***[[Chad Sorenson sandbox 1|Retinoblastoma Protein]]
***[[Molecular_Playground/Taxol|Taxol Information]]
***[[Telomerase Reverse Transcriptase]]
***[[User:Sarah Abdalla/Thioredoxin Reductase|Thioredoxin Reductase]]
***[[Molecular_Playground/TRAIL|Tumor-Necrosis Factor Apoptosis-Inducing Ligand]]
***[[Molecular_Playground/YKL-40|YKL-40]]


**Compromised Immune System
**Compromised Immune System
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**Diabetes & Hypoglycemia
**Diabetes & Hypoglycemia
***[[Molecular_Playground/Insulin|Insulin Information]]
*** [[See: Diabetes]]
***[[Sandbox 67|Insulin Structure]]
***[[User:Mary Ball/Leptin|Leptin]]
***[[Peroxisome Proliferator-Activated Receptors]]
***[[Molecular_Playground/YKL-40|YKL-40]]


**Digestive Diseases
**Digestive Diseases
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**Metabolic Disorders
**Metabolic Disorders
***[[Acid-beta-glucosidase]]
** See: [[Metabolic Disorders]]
***[[Molecular_playground/beta_2_microglobulin|ß-2 Microglobulin]]
***[[HMG-CoA Reductase]]
***[[Molecular_Playground/Human_PPCA|Protective Protein/Cathepsin A (PPCA)]]
***[[Molecular_Playground/Human_Protective_Protein_Cathepsin_A|Protective Protein/Cathepsin A (PPCA) 2]]
***[[Bacterial thiolase|Thiolase]]
***[[Treatment_of_Gaucher_disease]]
***[[Molecular_Playground/Velaglucerase|Velaglucerase]]
***[[Disulfide Connectivity of Velaglucerase|Velaglucerase Disulfide Connectivity]]


**Schizophrenia, Bipolar Depression, Insomnia, and Anxiety Disorders
**Schizophrenia, Bipolar Depression, Insomnia, and Anxiety Disorders
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**Viral Infection
**Viral Infection
***[[Molecular_Playground/T7_RNA_Polymerase_%287_mer_int%29| T7 RNA Polymerase]]
***[[Molecular_Playground/T7_RNA_Polymerase_%287_mer_int%29| T7 RNA Polymerase]]
*** HIV
*** See: [[Human Immunodeficiency Virus]]
****[[User:Eric Martz/Molecular Playground/HIVDrug|HIV-1 Drug]]
****[[HIV-1 protease|HIV-1 Protease]]
****[[User:Tsung-Yi_Lin/Sandbox|HIV-1 Protease Analysis]]
****[[HIV-1 Gag]]
****[[1gwp|HIV-1 Gag N-terminal Domain]]
****[[HIV-1 Gag Recruitment of Tsg101 and the Viral Budding Process]]
****[[HIV-1 NEF]]
****[[Molecular_Playground/HIV_Protease_Inhibitor|HIV-1 Protease Inhibitor]]
****[[HIV-1_Subtype_C_Protease|HIV-1 Subtype C Protease]]
****[[Retroviral Integrase]]
****[[Reverse Transcriptase]]
****[[Tetherin]]
*** Influenza
*** Influenza
**** [[Avian Influenza Neuraminidase, Tamiflu and Relenza]]
*** See: [[Influenza]]
**** [[Avian Influenza Neuraminidase, Tamiflu and Relenza]]
**** H1N1 Sequence Analyses
****** [[User:Michael_Strong/H1N1|H1N1 Swine Flu Sequence Analysis]]
****** [[User:Michael_Strong/H1N1/MP1/MSA|H1N1 Swine Flu Multiple Sequence Alignment]]
****** [[User:Michael Strong/H1N1/MP2/MSA|H1N1 Sequence Alignment of MP2 Protein]]
****** [[User:Michael_Strong/H1N1/PB2|H1N1 Sequence Alignment of PB2 Protein]]
****** [[User:Michael_Strong/H1N1/PB1|H1N1 Sequence Alignment of PB1 Protein]]
****** [[User:Michael_Strong/H1N1/NS2/MSA|H1N1 Sequence Alignment of NS2 Protein]]
****** [[User:Michael_Strong/H1N1/PA|H1N1 Sequence Alignment of PA Protein]]
****** [[User:Michael_Strong/H1N1/HA|H1N1 Sequence Alignment of HA Protein]]
****** [[User:Michael_Strong/H1N1/NP|H1N1 Sequence Alignment of NP Protein]]
****** [[User:Michael_Strong/H1N1/NA|H1N1 Sequence Alignment of NA Protein]]
****** [[User:Michael_Strong/H1N1/MP|H1N1 Sequence Alignment of MP Protein]]
****** [[User:Michael_Strong/H1N1/NS|H1N1 Sequence Alignment of NS Protein]]
**** [[SAndbox_159|Hemagglutinins]]
**** [[Influenza hemagglutinin]]
**** [[Molecular_Playground/Influenza_A_M2_transmembrane_domain|Influenza A M2 Transmembrane Domain]]
**** [[Proton Channels]] featuring a morph of the M2 proton channel of influenza.
**** [[Molecular Playground/Tamiflu|Tamiflu]]
**** [[Molecular Playground/Relenza|Relenza]]
*** [[Herpes Simplex Virus Thymidine Kinase]]
*** [[Herpes Simplex Virus Thymidine Kinase]]
*** [[NS5B|RNA Dependent RNA Polymerase from Hepatitis C Virus]]
*** [[NS5B|RNA Dependent RNA Polymerase from Hepatitis C Virus]]
}}
}}

Revision as of 19:47, 13 October 2010

AstraZeneca’s Nexium

The following is a list of major pharmaceutical compound targets, drugs, and information organized by disease.

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

David Canner, Thomas J. Stout, Eran Hodis, Wayne Decatur, Alexander Berchansky