P53: Difference between revisions

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Revision as of 11:39, 10 October 2010 view source Joel L. Sussman (talk \| contribs) ConfirmAccount, Editor, Journal, Mutation, Print3D, Tester, Bureaucrats, Administrators 7,980 edits No edit summary ← Older edit		Revision as of 11:39, 10 October 2010 view source Joel L. Sussman (talk \| contribs) ConfirmAccount, Editor, Journal, Mutation, Print3D, Tester, Bureaucrats, Administrators 7,980 edits No edit summary Newer edit →
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	The figure at the left shows the surface charge of the p53 DNA-binding domain. It is rich in arginine amino acids that interact with DNA, and this causes its surface to be positively charged. This domain recognizes specific regulatory sites on the DNA. The flexible structure of p53 allows it to bind to many different variants of binding sites, allowing it to regulate transcription at many places in the genome.		The figure at the left shows the surface charge of the p53 DNA-binding domain. It is rich in arginine amino acids that interact with DNA, and this causes its surface to be positively charged. This domain recognizes specific regulatory sites on the DNA. The flexible structure of p53 allows it to bind to many different variants of binding sites, allowing it to regulate transcription at many places in the genome.