B-RAF with PLX4032: Difference between revisions
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<applet load='3og7' size='800' color='white' frame='true' align='right' caption=' | <applet load='3og7' size='800' color='white' frame='true' align='right' caption='BRAF' /> | ||
<scene name='B-RAF_with_PLX4032/Plx_4032_only/2>PLX 4032</scene><br> | <scene name='B-RAF_with_PLX4032/Plx_4032_only/2'>PLX 4032</scene><br> | ||
<scene name='B-RAF_with_PLX4032/Atp/2'>ATP</scene><br> | <scene name='B-RAF_with_PLX4032/Atp/2'>ATP</scene><br> | ||
<scene name='B-RAF_with_PLX4032/Wild-type_b-raf/2'>Wild-Type B-RAF</scene> <br> | <scene name='B-RAF_with_PLX4032/Wild-type_b-raf/2'>Wild-Type B-RAF</scene> <br> | ||
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<scene name='B-RAF_with_PLX4032/Superposition3og71uwh/5'>Superposition close up</scene> <br> | <scene name='B-RAF_with_PLX4032/Superposition3og71uwh/5'>Superposition close up</scene> <br> | ||
<scene name='B-RAF_with_PLX4032/Superposition3og71uwh/2'>Superposition active site</scene> <br> | <scene name='B-RAF_with_PLX4032/Superposition3og71uwh/2'>Superposition active site</scene> <br> | ||
Revision as of 22:12, 7 October 2010
B-RAF with PLX4032B-RAF with PLX4032
PLX4032 is a newly synthesized drug that is being used to treat malignant melanoma with a specific mutation. The mutation is B-RAF^(V600E). This drug is highly selective for this mutation and will not bind to wild type B-RAF.
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