B-RAF with PLX4032: Difference between revisions
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<scene name='B-RAF_with_PLX4032/H-bond/1'>H-Bond Interaction Asp594 and PLX4032</scene> <br> | <scene name='B-RAF_with_PLX4032/H-bond/1'>H-Bond Interaction Asp594 and PLX4032</scene> <br> | ||
<scene name='B-RAF_with_PLX4032/Dfg_in_conformation/1'>DFG in</scene><br> | <scene name='B-RAF_with_PLX4032/Dfg_in_conformation/1'>DFG in</scene><br> | ||
<scene name='B-RAF_with_PLX4032/Phe_595_dfg_out/1'>DFG out</scene> | <scene name='B-RAF_with_PLX4032/Phe_595_dfg_out/1'>DFG out</scene><br> | ||
<scene name='B-RAF_with_PLX4032/Superposition3og71uwh/1'>Superposition</scene> | <scene name='B-RAF_with_PLX4032/Superposition3og71uwh/1'>Superposition</scene> | ||
<applet load='3og7' size='600' color='white' frame='true' align='left' caption='testcaption' /> | <applet load='3og7' size='600' color='white' frame='true' align='left' caption='testcaption' /> | ||
<applet load='1uwh' size='600' color='white' frame='true' align='right' caption='testcaption' /> | <applet load='1uwh' size='600' color='white' frame='true' align='right' caption='testcaption' /> | ||
Revision as of 20:34, 5 October 2010
B-RAF with PLX4032B-RAF with PLX4032
PLX4032 is a newly synthesized drug that is being used to treat malignant melanoma with a specific mutation. The mutation is B-RAF^(V600E). This drug is highly selective for this mutation and will not bind to wild type B-RAF.
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