1dzm: Difference between revisions
New page: left|200px<br /> <applet load="1dzm" size="450" color="white" frame="true" align="right" spinBox="true" caption="1dzm, resolution 1.93Å" /> '''PORCINE ODORANT BIN... |
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==About this Structure== | ==About this Structure== | ||
1DZM is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/ ]] with BZM as [[http://en.wikipedia.org/wiki/ligand ligand]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1DZM OCA]]. | 1DZM is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]] with BZM as [[http://en.wikipedia.org/wiki/ligand ligand]]. Structure known Active Sites: AC1 and AC2. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1DZM OCA]]. | ||
==Reference== | ==Reference== | ||
Complexes of porcine odorant binding protein with odorant molecules belonging to different chemical classes., Vincent F, Spinelli S, Ramoni R, Grolli S, Pelosi P, Cambillau C, Tegoni M, J Mol Biol. 2000 Jun 30;300(1):127-39. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10864504 10864504] | Complexes of porcine odorant binding protein with odorant molecules belonging to different chemical classes., Vincent F, Spinelli S, Ramoni R, Grolli S, Pelosi P, Cambillau C, Tegoni M, J Mol Biol. 2000 Jun 30;300(1):127-39. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10864504 10864504] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Sus scrofa]] | |||
[[Category: Cambillau, C.]] | [[Category: Cambillau, C.]] | ||
[[Category: Grolli, S.]] | [[Category: Grolli, S.]] | ||
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[[Category: odorant binding protein]] | [[Category: odorant binding protein]] | ||
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Revision as of 11:56, 30 October 2007
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PORCINE ODORANT BINDING PROTEIN COMPLEXED WITH BENZOIC ACID PHENYLMETHYLESTER
OverviewOverview
Porcine odorant binding protein (pOBP) is a monomer of 157 amino acid, residues, purified in abundance from pig nasal mucosa. In contrast to the, observation on lipocalins as retinol binding protein (RBP), major urinary, protein (MUP) or bovine odorant binding protein (bOBP), no naturally, occurring ligand was found in the beta-barrel cavity of pOBP. Porcine OBP, was therefore chosen as a simple model for structure/function studies with, odorant molecules. In competition experiments with tritiated pyrazine, the, affinity of pOBP towards several odorant molecules belonging to different, chemical classes has been found to be of the micromolar order, with a 1:1, stoichiometry. The X-ray structures of pOBP complexed to these molecules, were determined at resolution between 2.15 and 1.4 A. As ... [(full description)]
About this StructureAbout this Structure
1DZM is a [Single protein] structure of sequence from [Sus scrofa] with BZM as [ligand]. Structure known Active Sites: AC1 and AC2. Full crystallographic information is available from [OCA].
ReferenceReference
Complexes of porcine odorant binding protein with odorant molecules belonging to different chemical classes., Vincent F, Spinelli S, Ramoni R, Grolli S, Pelosi P, Cambillau C, Tegoni M, J Mol Biol. 2000 Jun 30;300(1):127-39. PMID:10864504
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