B-RAF with PLX4032: Difference between revisions

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<scene name='B-RAF_with_PLX4032/Plx_4032_only/1'>PLX 4032</scene><br>
<scene name='B-RAF_with_PLX4032/Plx_4032_only/1'>PLX 4032</scene><br>
<scene name='B-RAF_with_PLX4032/V600e_mutation/1'>V600E mutation</scene><br>
<scene name='B-RAF_with_PLX4032/V600e_mutation/1'>V600E mutation</scene><br>
<scene name='B-RAF_with_PLX4032/Plx4032_n/1'>TextToBeDisplayed</scene>
<scene name='B-RAF_with_PLX4032/Dfg_in_conformation/1'>DFG in</scene><br>
<scene name='B-RAF_with_PLX4032/Dfg_in_conformation/1'>DFG in</scene><br>
<scene name='B-RAF_with_PLX4032/Phe_595_dfg_out/1'>DFG out</scene>
<scene name='B-RAF_with_PLX4032/Phe_595_dfg_out/1'>DFG out</scene>
<applet load='3og7' size='700' color='white' frame='true' align='center' caption='testcaption' />
<applet load='3og7' size='700' color='white' frame='true' align='center' caption='testcaption' />
<applet load='1uwh' size='700' color='white' frame='true' align='center' caption='testcaption' />
<applet load='1uwh' size='700' color='white' frame='true' align='center' caption='testcaption' />

Revision as of 04:35, 29 September 2010

B-RAF with PLX4032B-RAF with PLX4032

PLX4032 is a newly synthesized drug that is being used to treat malignant melanonma with a specific mutation. The mutation is B-RAF^(V600E). This drug is highly selective for this mutation and will not bind to wild type B-RAF.





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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Jens Hemmingsen, J.D. Woodruff, Michal Harel