3ekk: Difference between revisions

Revision as of 11:13, 22 September 2010

This article has been automatically seeded. Changes to this page should pertain to the PDB entry only and not to the protein or biomolecule in general.

File:3ekk.png

Template:STRUCTURE 3ekk

Insulin receptor kinase complexed with an inhibitorInsulin receptor kinase complexed with an inhibitor

Template:ABSTRACT PUBMED 19056263

About this StructureAbout this Structure

3EKK is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

^{[xtra 1]}

↑ Chamberlain SD, Wilson JW, Deanda F, Patnaik S, Redman AM, Yang B, Shewchuk L, Sabbatini P, Leesnitzer MA, Groy A, Atkins C, Gerding R, Hassell AM, Lei H, Mook RA Jr, Moorthy G, Rowand JL, Stevens KL, Kumar R, Shotwell JB. Discovery of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidines: Potent inhibitors of the IGF-1R receptor tyrosine kinase. Bioorg Med Chem Lett. 2008 Nov 18. PMID:19056263 doi:S0960-894X(08)01424-8

Page seeded by OCA on Wed Sep 22 11:22:47 2010

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

[1] Chamberlain SD, Wilson JW, Deanda F, Patnaik S, Redman AM, Yang B, Shewchuk L, Sabbatini P, Leesnitzer MA, Groy A, Atkins C, Gerding R, Hassell AM, Lei H, Mook RA Jr, Moorthy G, Rowand JL, Stevens KL, Kumar R, Shotwell JB. Discovery of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidines: Potent inhibitors of the IGF-1R receptor tyrosine kinase. Bioorg Med Chem Lett. 2008 Nov 18. PMID:19056263 doi:S0960-894X(08)01424-8

[xtra 1]

@@ Line 18: / Line 18: @@
 -->
 {{ABSTRACT_PUBMED_19056263}}
-==Disease==
-Known disease associated with this structure: Diabetes mellitus, insulin-resistant, with acanthosis nigricans OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147670 147670]], Hyperinsulinemic hypoglycemia, familial, 5 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147670 147670]], Leprechaunism OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147670 147670]], Rabson-Mendenhall syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147670 147670]]
 ==About this Structure==
-EKK is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EKK OCA].
+EKK is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EKK OCA].
 ==Reference==
-Discovery of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidines: Potent inhibitors of the IGF-1R receptor tyrosine kinase., Chamberlain SD, Wilson JW, Deanda F, Patnaik S, Redman AM, Yang B, Shewchuk L, Sabbatini P, Leesnitzer MA, Groy A, Atkins C, Gerding R, Hassell AM, Lei H, Mook RA Jr, Moorthy G, Rowand JL, Stevens KL, Kumar R, Shotwell JB, Bioorg Med Chem Lett. 2008 Nov 18. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/19056263 19056263]
+<ref group="xtra">PMID:19056263</ref><references group="xtra"/>
 [[Category: Homo sapiens]]
 [[Category: Receptor protein-tyrosine kinase]]
-[[Category: Single protein]]
+[[Category: Atkins, C.]]
-[[Category: Pdbx_ordinal=, <PDBx:audit_author.]]
+[[Category: Chamberlain, S.]]
+[[Category: Deanda, F.]]
+[[Category: Dumble, M.]]
+[[Category: Gerding, R.]]
+[[Category: Groy, A.]]
+[[Category: Korenchuk, S.]]
+[[Category: Kumar, R.]]
+[[Category: Lei, H.]]
+[[Category: Mook, R.]]
+[[Category: Moorthy, G.]]
+[[Category: Redman, A.]]
+[[Category: Rowland, J.]]
+[[Category: Sabbatini, P.]]
+[[Category: Shewchuk, L.]]
 [[Category: Alternative splicing]]
 [[Category: Atp-binding]]
@@ Line 50: / Line 60: @@
 [[Category: Tyrosine-protein kinase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan  7 20:06:42 2009''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 22 11:22:47 2010''