2xk2: Difference between revisions

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New page: '''Unreleased structure''' The entry 2xk2 is ON HOLD Authors: Murray, C.W., Carr, M.G., Callaghan, O., Chessari, G., Congreve, M., Cowan, S., Coyle, J.E., Downham, R., Figueroa, E., Fre...
 
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'''Unreleased structure'''
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[[Image:2xk2.jpg|left|200px]]


The entry 2xk2 is ON HOLD
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{{STRUCTURE_2xk2|  PDB=2xk2 |  SCENE=  }}


Authors: Murray, C.W., Carr, M.G., Callaghan, O., Chessari, G., Congreve, M., Cowan, S., Coyle, J.E., Downham, R., Figueroa, E., Frederickson, M., Graham, B., McMenamin, R., OBrien, M.A., Patel, S., Phillips, T.R., Williams, G., Woodhead, A.J., Woolford, A.J.A.
===STRUCTRE OF HSP90 WITH SMALL MOLECULE INHIBITOR BOUND===


Description: Structre of HSP90 with small molecule inhibitor bound


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 14 16:01:35 2010''
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{{ABSTRACT_PUBMED_20718493}}
 
==About this Structure==
2XK2 is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XK2 OCA].
 
==Reference==
<ref group="xtra">PMID:20718493</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Callaghan, O.]]
[[Category: Carr, M G.]]
[[Category: Chessari, G.]]
[[Category: Congreve, M.]]
[[Category: Cowan, S.]]
[[Category: Coyle, J E.]]
[[Category: Downham, R.]]
[[Category: Figueroa, E.]]
[[Category: Frederickson, M.]]
[[Category: Graham, B.]]
[[Category: Mcmenamin, R.]]
[[Category: Murray, C W.]]
[[Category: Obrien, M A.]]
[[Category: Patel, S.]]
[[Category: Phillips, T R.]]
[[Category: Williams, G.]]
[[Category: Woodhead, A J.]]
[[Category: Woolford, A J.A.]]
[[Category: Chaperone]]
[[Category: Stress response]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep  1 09:46:13 2010''

Revision as of 08:38, 1 September 2010

File:2xk2.jpg

Template:STRUCTURE 2xk2

STRUCTRE OF HSP90 WITH SMALL MOLECULE INHIBITOR BOUNDSTRUCTRE OF HSP90 WITH SMALL MOLECULE INHIBITOR BOUND

Template:ABSTRACT PUBMED 20718493

About this StructureAbout this Structure

2XK2 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Murray CW, Carr MG, Callaghan O, Chessari G, Congreve M, Cowan S, Coyle JE, Downham R, Figueroa E, Frederickson M, Graham B, McMenamin R, O'Brien MA, Patel S, Phillips TR, Williams G, Woodhead AJ, Woolford AJ. Fragment-based drug discovery applied to hsp90. Discovery of two lead series with high ligand efficiency. J Med Chem. 2010 Aug 26;53(16):5942-55. PMID:20718493 doi:10.1021/jm100059d

Page seeded by OCA on Wed Sep 1 09:46:13 2010

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