2jhp: Difference between revisions
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[[Image:2jhp.gif|left|200px]]<br /> | [[Image:2jhp.gif|left|200px]]<br /><applet load="2jhp" size="450" color="white" frame="true" align="right" spinBox="true" | ||
<applet load="2jhp" size="450" color="white" frame="true" align="right" spinBox="true" | |||
caption="2jhp, resolution 2.50Å" /> | caption="2jhp, resolution 2.50Å" /> | ||
'''THE STRUCTURE OF BLUETONGUE VIRUS VP4 REVEALS A MULTIFUNCTIONAL RNA-CAPPING PRODUCTION-LINE'''<br /> | '''THE STRUCTURE OF BLUETONGUE VIRUS VP4 REVEALS A MULTIFUNCTIONAL RNA-CAPPING PRODUCTION-LINE'''<br /> | ||
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==About this Structure== | ==About this Structure== | ||
2JHP is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bluetongue_virus_10_(isolate_usa) Bluetongue virus 10 (isolate usa)] with SAH and GUN as [http://en.wikipedia.org/wiki/ligands ligands]. | 2JHP is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bluetongue_virus_10_(isolate_usa) Bluetongue virus 10 (isolate usa)] with SAH and GUN as [http://en.wikipedia.org/wiki/ligands ligands]. Known structural/functional Site: <scene name='pdbsite=AC1:Gun Binding Site For Chain A'>AC1</scene>. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2JHP OCA]. | ||
==Reference== | ==Reference== | ||
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[[Category: virion protein]] | [[Category: virion protein]] | ||
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Dec 18 20:09:49 2007'' | ||
Revision as of 21:00, 18 December 2007
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THE STRUCTURE OF BLUETONGUE VIRUS VP4 REVEALS A MULTIFUNCTIONAL RNA-CAPPING PRODUCTION-LINE
OverviewOverview
Eukaryotic organisms cap the 5' ends of their messenger RNAs by a series, of four chemical reactions. Some viruses achieve this using a single, molecule; the crystal structure of such an enzyme from bluetongue virus, reveals an elongated modular architecture that provides a scaffold for an, assemblage of active sites, two contributed by a domain of novel, structure.
About this StructureAbout this Structure
2JHP is a Single protein structure of sequence from Bluetongue virus 10 (isolate usa) with SAH and GUN as ligands. Known structural/functional Site: . Full crystallographic information is available from OCA.
ReferenceReference
Bluetongue virus VP4 is an RNA-capping assembly line., Sutton G, Grimes JM, Stuart DI, Roy P, Nat Struct Mol Biol. 2007 May;14(5):449-51. Epub 2007 Apr 8. PMID:17417654
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