1rcx: Difference between revisions

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New page: left|200px<br /> <applet load="1rcx" size="450" color="white" frame="true" align="right" spinBox="true" caption="1rcx, resolution 2.4Å" /> '''NON-ACTIVATED SPINAC...
 
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==About this Structure==
==About this Structure==
1RCX is a [[http://en.wikipedia.org/wiki/Protein_complex Protein complex]] structure of sequences from [[http://en.wikipedia.org/wiki/Spinacia_oleracea Spinacia oleracea]] with RUB as [[http://en.wikipedia.org/wiki/ligand ligand]]. The following page contains interesting information on the relation of 1RCX with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb11_1.html Rubisco]]. Active as [[http://en.wikipedia.org/wiki/ ]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.39 4.1.1.39]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1RCX OCA]].  
1RCX is a [[http://en.wikipedia.org/wiki/Protein_complex Protein complex]] structure of sequences from [[http://en.wikipedia.org/wiki/Spinacia_oleracea Spinacia oleracea]] with RUB as [[http://en.wikipedia.org/wiki/ligand ligand]]. The following page contains interesting information on the relation of 1RCX with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb11_1.html Rubisco]]. Active as [[http://en.wikipedia.org/wiki/Ribulose-bisphosphate_carboxylase Ribulose-bisphosphate carboxylase]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.39 4.1.1.39]]. Structure known Active Sites: ACB, ACE, ACH, ACK, ACL, ACO, ACR and ACV. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1RCX OCA]].  


==Reference==
==Reference==
The structure of the complex between rubisco and its natural substrate ribulose 1,5-bisphosphate., Taylor TC, Andersson I, J Mol Biol. 1997 Jan 31;265(4):432-44. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9034362 9034362]
The structure of the complex between rubisco and its natural substrate ribulose 1,5-bisphosphate., Taylor TC, Andersson I, J Mol Biol. 1997 Jan 31;265(4):432-44. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9034362 9034362]
[[Category: Protein complex]]
[[Category: Protein complex]]
[[Category: Ribulose-bisphosphate carboxylase]]
[[Category: Rubisco]]
[[Category: Rubisco]]
[[Category: Spinacia oleracea]]
[[Category: Spinacia oleracea]]
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[[Category: lyase (carbon-carbon)]]
[[Category: lyase (carbon-carbon)]]


''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Oct 29 16:57:50 2007''
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 10:53:57 2007''

Revision as of 11:49, 30 October 2007

File:1rcx.gif


1rcx, resolution 2.4Å

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NON-ACTIVATED SPINACH RUBISCO IN COMPLEX WITH ITS SUBSTRATE RIBULOSE-1,5-BISPHOSPHATE

OverviewOverview

The three-dimensional structure of the complex of ribulose, 1,5-bisphosphate carboxylase/oxygenase (rubisco; EC 4.1.1.39) from spinach, with its natural substrate ribulose 1,5-bisphosphate (RuBP) has been, determined both under activating and non-activating conditions by X-ray, crystallography to a resolution of 2.1 A and 2.4 A, respectively. Under, activating conditions, the use of calcium instead of magnesium as the, activator metal ion enabled us to trap the substrate in a stable complex, for crystallographic analysis. Comparison of the structure of the, activated and the non-activated RuBP complexes shows a tighter binding for, the substrate in the non-activated form of the enzyme, in line with, previous solution studies. In the non-activated complex, the substrate, triggers isolation ... [(full description)]

About this StructureAbout this Structure

1RCX is a [Protein complex] structure of sequences from [Spinacia oleracea] with RUB as [ligand]. The following page contains interesting information on the relation of 1RCX with [Rubisco]. Active as [Ribulose-bisphosphate carboxylase], with EC number [4.1.1.39]. Structure known Active Sites: ACB, ACE, ACH, ACK, ACL, ACO, ACR and ACV. Full crystallographic information is available from [OCA].

ReferenceReference

The structure of the complex between rubisco and its natural substrate ribulose 1,5-bisphosphate., Taylor TC, Andersson I, J Mol Biol. 1997 Jan 31;265(4):432-44. PMID:9034362

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