1rcx: Difference between revisions
New page: left|200px<br /> <applet load="1rcx" size="450" color="white" frame="true" align="right" spinBox="true" caption="1rcx, resolution 2.4Å" /> '''NON-ACTIVATED SPINAC... |
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==About this Structure== | ==About this Structure== | ||
1RCX is a [[http://en.wikipedia.org/wiki/Protein_complex Protein complex]] structure of sequences from [[http://en.wikipedia.org/wiki/Spinacia_oleracea Spinacia oleracea]] with RUB as [[http://en.wikipedia.org/wiki/ligand ligand]]. The following page contains interesting information on the relation of 1RCX with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb11_1.html Rubisco]]. Active as [[http://en.wikipedia.org/wiki/ ]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.39 4.1.1.39]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1RCX OCA]]. | 1RCX is a [[http://en.wikipedia.org/wiki/Protein_complex Protein complex]] structure of sequences from [[http://en.wikipedia.org/wiki/Spinacia_oleracea Spinacia oleracea]] with RUB as [[http://en.wikipedia.org/wiki/ligand ligand]]. The following page contains interesting information on the relation of 1RCX with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb11_1.html Rubisco]]. Active as [[http://en.wikipedia.org/wiki/Ribulose-bisphosphate_carboxylase Ribulose-bisphosphate carboxylase]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.39 4.1.1.39]]. Structure known Active Sites: ACB, ACE, ACH, ACK, ACL, ACO, ACR and ACV. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1RCX OCA]]. | ||
==Reference== | ==Reference== | ||
The structure of the complex between rubisco and its natural substrate ribulose 1,5-bisphosphate., Taylor TC, Andersson I, J Mol Biol. 1997 Jan 31;265(4):432-44. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9034362 9034362] | The structure of the complex between rubisco and its natural substrate ribulose 1,5-bisphosphate., Taylor TC, Andersson I, J Mol Biol. 1997 Jan 31;265(4):432-44. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9034362 9034362] | ||
[[Category: Protein complex]] | [[Category: Protein complex]] | ||
[[Category: Ribulose-bisphosphate carboxylase]] | |||
[[Category: Rubisco]] | [[Category: Rubisco]] | ||
[[Category: Spinacia oleracea]] | [[Category: Spinacia oleracea]] | ||
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[[Category: lyase (carbon-carbon)]] | [[Category: lyase (carbon-carbon)]] | ||
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 10:53:57 2007'' |
Revision as of 11:49, 30 October 2007
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NON-ACTIVATED SPINACH RUBISCO IN COMPLEX WITH ITS SUBSTRATE RIBULOSE-1,5-BISPHOSPHATE
OverviewOverview
The three-dimensional structure of the complex of ribulose, 1,5-bisphosphate carboxylase/oxygenase (rubisco; EC 4.1.1.39) from spinach, with its natural substrate ribulose 1,5-bisphosphate (RuBP) has been, determined both under activating and non-activating conditions by X-ray, crystallography to a resolution of 2.1 A and 2.4 A, respectively. Under, activating conditions, the use of calcium instead of magnesium as the, activator metal ion enabled us to trap the substrate in a stable complex, for crystallographic analysis. Comparison of the structure of the, activated and the non-activated RuBP complexes shows a tighter binding for, the substrate in the non-activated form of the enzyme, in line with, previous solution studies. In the non-activated complex, the substrate, triggers isolation ... [(full description)]
About this StructureAbout this Structure
1RCX is a [Protein complex] structure of sequences from [Spinacia oleracea] with RUB as [ligand]. The following page contains interesting information on the relation of 1RCX with [Rubisco]. Active as [Ribulose-bisphosphate carboxylase], with EC number [4.1.1.39]. Structure known Active Sites: ACB, ACE, ACH, ACK, ACL, ACO, ACR and ACV. Full crystallographic information is available from [OCA].
ReferenceReference
The structure of the complex between rubisco and its natural substrate ribulose 1,5-bisphosphate., Taylor TC, Andersson I, J Mol Biol. 1997 Jan 31;265(4):432-44. PMID:9034362
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