4pgm: Difference between revisions
New page: left|200px<br /> <applet load="4pgm" size="450" color="white" frame="true" align="right" spinBox="true" caption="4pgm, resolution 2.3Å" /> '''SACCHAROMYCES CEREVI... |
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==About this Structure== | ==About this Structure== | ||
4PGM is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]]. Active as [[http://en.wikipedia.org/wiki/ ]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.2.1 5.4.2.1]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=4PGM OCA]]. | 4PGM is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]]. Active as [[http://en.wikipedia.org/wiki/Phosphoglycerate_mutase Phosphoglycerate mutase]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.2.1 5.4.2.1]]. Structure known Active Site: CIC. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=4PGM OCA]]. | ||
==Reference== | ==Reference== | ||
The 2.3 A X-ray crystal structure of S. cerevisiae phosphoglycerate mutase., Rigden DJ, Alexeev D, Phillips SE, Fothergill-Gilmore LA, J Mol Biol. 1998 Feb 20;276(2):449-59. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9512715 9512715] | The 2.3 A X-ray crystal structure of S. cerevisiae phosphoglycerate mutase., Rigden DJ, Alexeev D, Phillips SE, Fothergill-Gilmore LA, J Mol Biol. 1998 Feb 20;276(2):449-59. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9512715 9512715] | ||
[[Category: Phosphoglycerate mutase]] | |||
[[Category: Saccharomyces cerevisiae]] | [[Category: Saccharomyces cerevisiae]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: transferase (phosphoryl)]] | [[Category: transferase (phosphoryl)]] | ||
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Revision as of 11:48, 30 October 2007
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SACCHAROMYCES CEREVISIAE PHOSPHOGLYCERATE MUTASE
OverviewOverview
The high resolution crystal structure of Saccharomyces cerevisiae, phosphoglycerate mutase has been determined. This structure shows, important differences from the lower resolution structure deposited in, 1982. The crystal used to determine the new structure was of a different, form, having spacegroup P2(1). The model was refined to a crystallographic, R-factor of 18.9% and a free R-factor of 28.4% using all data between 25, and 2.3 A and employing a bulk solvent correction. The enzyme is a, tetramer of identical, 246 amino acid subunits, whose structure is, revealed to be a dimer of dimers, with four independent active sites, located well away from the subunit contacts. Each subunit contains two, domains, the larger with a typical nucleotide binding fold, although, phosphoglycerate ... [(full description)]
About this StructureAbout this Structure
4PGM is a [Single protein] structure of sequence from [Saccharomyces cerevisiae]. Active as [Phosphoglycerate mutase], with EC number [5.4.2.1]. Structure known Active Site: CIC. Full crystallographic information is available from [OCA].
ReferenceReference
The 2.3 A X-ray crystal structure of S. cerevisiae phosphoglycerate mutase., Rigden DJ, Alexeev D, Phillips SE, Fothergill-Gilmore LA, J Mol Biol. 1998 Feb 20;276(2):449-59. PMID:9512715
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