Porin: Difference between revisions
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
[[Image:Ompc.png|left|250px|thumb|Crystal structure of Porin OmpC from ''E. coli'', [[2j1n]]]] | [[Image:Ompc.png|left|250px|thumb|Crystal structure of Porin OmpC from ''E. coli'', [[2j1n]]]] | ||
{{STRUCTURE_2j1n| PDB=2j1n | SIZE=300| SCENE= |right|CAPTION=Porin OmpC from ''E. coli'', [[2j1n]] }} | {{STRUCTURE_2j1n| PDB=2j1n | SIZE=300| SCENE=Porin/Cv/1 |right|CAPTION=Porin OmpC from ''E. coli'', [[2j1n]] }} | ||
'''Porin''' | |||
'''Porins''' or '''Outer Membrane Proteins (Omps)''' act as channels which allow passive diffusion of sugars, ions and amino acids. They are beta barrel proteins which traverse the cell membrane. In E. coli they are named according to their genes: C, F, G (OmpC, OmpF, Ompg). '''Voltage-Dependent Anion Channel (VDAC)''' is ion channel Omp found in outer mitochondrial membrane. In Pseudomonas aeruginosa the porin gene products are named OprD, OprK, OprP. The images at the left and at the right correspond to one representative Porin structure, ''i.e.'' crystal structure osmoporin OmpC from Escherichia coli ([[1kcf]]). OmpC has three beta-barrels associated to form a <scene name='Porin/Cv/2'>tight trimer</scene> <ref>PMID:16949612</ref>. | |||
{{TOC limit|limit=2}} | |||
== Porin == | |||
[[2xe5]], [[2xe1]], [[2xe2]], [[2xe3]], [[2j1n]] – EcOmpC – ''Escherichia coli''<br /> | |||
[[2j4u]] – EcOmpC+lactotransferrin fragment<br /> | |||
[[3k19]], [[3k1b]], [[2zfg]], [[1omf]], [[1op]]f – EcOmpF<br /> | |||
[[1hxt]], [[1hxu]], [[1hxx]], [[1bt9]], [[1gfm]], [[1gfn]], [[1gfo]], [[1gfp]], [[1gfq]], [[1mpf]] – EcOmpF (mutant)<br /> | |||
[[2zld]] – EcOmpF+colicin E3<br /> | |||
[[3hw9]], [[3hwb]] – EcOmpF+ions<br /> | |||
[[3fyx]] – EcOmpF+dibenzo-18-crown-6<br /> | |||
[[2iwv]], [[2iww]], [[2f1c]] - EcOmpG<br /> | |||
[[2wjq]], [[2wjr]] – EcOmp NANC<br /> | |||
[[1af6]], [[1mpq]], [[1mpm]], [[1mpn]], [[1mpo]] – EcOmp LAMB+sugars<br /> | |||
[[1pho]] - EcOmp<br /> | |||
[[3a2r]] – NmOmpB – ''Neisseria meningitides''<br /> | |||
[[3a2s]], [[3a2t]] – NmOmpB+sugars<br /> | |||
[[3a2u]] - NmOmpB+AMPPNP<br /> | |||
[[3jty]] – Omp – ''Pseudomonas fluorescens''<br /> | |||
[[2qtk]] – PaOprK – ''Pseudomonas aeruginosa''<br /> | |||
[[2odj]] - PaOprD<br /> | |||
[[2o4v]] – PaOprP+phosphate<br /> | |||
[[2v9u]] – MsOmp rim domain – ''Mycobacteria smegmatis''<br /> | |||
[[1uun]] – MsOmp (mutant)<br /> | |||
[[2fgq]] – DaOmp32+malate – ''Delftia acidovorans''<br /> | |||
[[2fgr]] - DaOmp32<br /> | |||
[[1e54]] – Omp32+sulfate – ''Comamonas acidovorans''<br /> | |||
[[1oh2]], [[1a0t]] – StOmp+sucrose – ''Salmonella typhimurium''<br /> | |||
[[1a0s]], [[1mpr]] - StOmp<br /> | |||
[[1h6s]] – RbOmp+inserted sequence – ''Rhodopseudomonas blastica''<br /> | |||
[[2prn]], [[1bh3]], [[3prn]], [[5prn]], [[6prn]], [[7prn]], [[8prn]] – RbOmp (mutant)<br /> | |||
[[1prn]] - RbOmp<br /> | |||
[[1osm]] – OmpK36 – ''Klebsiella pneumoniae''<br /> | |||
[[2por]], [[3por]] – Omp – ''Rhodobacter capsulatus''<br /> | |||
== Voltage-Dependent Anion Channel == | |||
[[2jk4]] – hVDAC-1 – human<br /> | |||
[[2k4t]] - hVDAC-1 - NMR<br /> | |||
[[3emn]] – VDAC-1 - mouse<br /> | |||
==References== | |||
<references /> | |||