3lxl: Difference between revisions

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{{Seed}}
{{Seed}}
[[Image:3lxl.jpg|left|200px]]
[[Image:3lxl.png|left|200px]]


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{{ABSTRACT_PUBMED_20478313}}
{{ABSTRACT_PUBMED_20478313}}
==Disease==
Known disease associated with this structure: SCID, autosomal recessive, T-negative/B-positive type OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600173 600173]]


==About this Structure==
==About this Structure==
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[[Category: Benson, T E.]]
[[Category: Benson, T E.]]
[[Category: Chrencik, J E.]]
[[Category: Chrencik, J E.]]
[[Category: Alternative splicing]]
[[Category: Atp-binding]]
[[Category: Atp-binding]]
[[Category: Cancer]]
[[Category: Cancer]]
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[[Category: Pan inhibitor]]
[[Category: Pan inhibitor]]
[[Category: Phosphoprotein]]
[[Category: Phosphoprotein]]
[[Category: Polymorphism]]
[[Category: Scid]]
[[Category: Scid]]
[[Category: Sh2 domain]]
[[Category: Sh2 domain]]
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[[Category: Tyrosine-protein kinase]]
[[Category: Tyrosine-protein kinase]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun  2 08:36:02 2010''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 28 12:15:58 2010''

Revision as of 11:09, 28 July 2010

File:3lxl.png

Template:STRUCTURE 3lxl

Structural and Thermodynamic Characterization of the TYK2 and JAK3 Kinase Domains in Complex with CP-690550 and CMP-6Structural and Thermodynamic Characterization of the TYK2 and JAK3 Kinase Domains in Complex with CP-690550 and CMP-6

Template:ABSTRACT PUBMED 20478313

About this StructureAbout this Structure

3LXL is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Chrencik JE, Patny A, Leung IK, Korniski B, Emmons TL, Hall T, Weinberg RA, Gormley JA, Williams JM, Day JE, Hirsch JL, Kiefer JR, Leone JW, Fischer HD, Sommers CD, Huang HC, Jacobsen EJ, Tenbrink RE, Tomasselli AG, Benson TE. Structural and thermodynamic characterization of the TYK2 and JAK3 kinase domains in complex with CP-690550 and CMP-6. J Mol Biol. 2010 Jul 16;400(3):413-33. Epub 2010 May 15. PMID:20478313 doi:10.1016/j.jmb.2010.05.020

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