Urea transporter: Difference between revisions
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The structure revealed <scene name='Urea_transporter/3k3fdefault/1a> monomer of the urea transporter</scene> in the asymmetric unit. | The structure revealed <scene name='Urea_transporter/3k3fdefault/1a> monomer of the urea transporter</scene> in the asymmetric unit. | ||
However, the urea transporter crystallized as <scene name='Urea_transporter/3k3f_trimer/1'> | However, the urea transporter crystallized as <scene name='Urea_transporter/3k3f_trimer/1'>a homotrimer that corresponds to its functional biological state</scene>, and this is seen when considering the crystallographic three-fold symmetry axis. | ||
To help give a better idea of how the urea transporter is oriented in the membrane lipid bilayer, <scene name='Urea_transporter/Opm_3k3f/3'>a slab representative of hydrophobic core of the lipid bilayer</scene> as calculated by the [http://opm.phar.umich.edu/protein.php?pdbid=3kg2 Orientations of Proteins in Membranes database](University of Michigan, USA) is shown with the red patch of spheres indicating the boundary of the hydrophobic core closet to the outside of the cell and the dark blue patch of spheres indicating the boundary closest to the inside of the cell. | To help give a better idea of how the urea transporter is oriented in the membrane lipid bilayer, <scene name='Urea_transporter/Opm_3k3f/3'>a slab representative of hydrophobic core of the lipid bilayer</scene> as calculated by the [http://opm.phar.umich.edu/protein.php?pdbid=3kg2 Orientations of Proteins in Membranes database](University of Michigan, USA) is shown with the red patch of spheres indicating the boundary of the hydrophobic core closet to the outside of the cell and the dark blue patch of spheres indicating the boundary closest to the inside of the cell. | ||
[[Image:Opm_periplasmic_topology.gif]] <!--I got this from Eric Martz's [[Mechanosensitive channels: opening and closing]]--> | [[Image:Opm_periplasmic_topology.gif]] <!--I got this from Eric Martz's [[Mechanosensitive channels: opening and closing]]--> | ||
==PDB entry== | ==PDB entry== | ||