User talk:Johan sunryd/sandbox 1: Difference between revisions

Revision as of 05:03, 26 April 2010 view source Johan Sunryd (talk \| contribs) 16 edits No edit summary ← Older edit		Revision as of 04:55, 30 April 2010 view source Johan Sunryd (talk \| contribs) 16 edits No edit summary Newer edit →
Line 1:		Line 1:


	Alpha-mannosidases I is a human protein that reside in the endoplasmic reticulum(ER) lumen. ERMan1 is part of the class 1 glycosylhydrolase family 47 group of proteins and sports a Tim-barrel fold. In the ER N-linked glycans are used as indicators of how well a client protein is folded. ERMan1 functions by slowly trimming N-linked glycans, giving the protein at hand a defined window of time before the client protein can be targeted for degradation by other ER proteins.		Alpha-mannosidases I is a human protein that reside in the endoplasmic reticulum(ER) lumen. ERMan1 is part of the class 1 glycosylhydrolase family 47 group of proteins and sports a Tim-barrel fold. In the ER N-linked glycans are used as indicators of how well a client protein is folded. ERMan1 functions by slowly trimming N-linked glycans, giving the protein at hand a defined window of time before the client protein can be targeted for degradation by other ER proteins.
Line 15:		Line 14:


	Molecular Playground banner: A catalytic timer for protein degradation.		"Molecular Playground banner: A catalytic timer for protein degradation."