3l3a: Difference between revisions

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'''Unreleased structure'''
{{Seed}}
[[Image:3l3a.jpg|left|200px]]


The entry 3l3a is ON HOLD until Paper Publication
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{{STRUCTURE_3l3a|  PDB=3l3a  |  SCENE=  }}


Authors: Olland, A.M., Chopra, R.
===Bace-1 with the aminopyridine Compound 32===


Description: Bace-1 with the aminopyridine Compound 32


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{{ABSTRACT_PUBMED_20223661}}
 
==About this Structure==
3L3A is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L3A OCA].
 
==Reference==
<ref group="xtra">PMID:20223661</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Memapsin 2]]
[[Category: Chopra, R.]]
[[Category: Olland, A M.]]
[[Category: Aminopyridine]]
[[Category: Aspartyl protease]]
[[Category: Bace-1]]
[[Category: Beta-secretase]]
[[Category: Disulfide bond]]
[[Category: Hydrolase]]
[[Category: Inhibitor]]
[[Category: Protease]]
[[Category: Transmembrane]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 28 10:55:11 2010''

Revision as of 10:55, 28 April 2010

File:3l3a.jpg

Template:STRUCTURE 3l3a

Bace-1 with the aminopyridine Compound 32Bace-1 with the aminopyridine Compound 32

Template:ABSTRACT PUBMED 20223661

About this StructureAbout this Structure

3L3A is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Malamas MS, Barnes K, Hui Y, Johnson M, Lovering F, Condon J, Fobare W, Solvibile W, Turner J, Hu Y, Manas ES, Fan K, Olland A, Chopra R, Bard J, Pangalos MN, Reinhart P, Robichaud AJ. Novel pyrrolyl 2-aminopyridines as potent and selective human beta-secretase (BACE1) inhibitors. Bioorg Med Chem Lett. 2010 Apr 1;20(7):2068-73. Epub 2010 Feb 23. PMID:20223661 doi:10.1016/j.bmcl.2010.02.075

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