User:Cameron Evans/Sandbox 1: Difference between revisions
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===Specificity=== | ===Specificity=== | ||
<scene name='User:Cameron_Evans/Sandbox_1/1bgv_spec_pocket/2'>Specific interactions of ''Clostridium symbiosum'' GluDH to Glu</scene> are made up of polar interactions from K89 and S380 (to the gamma carbonyl) and hydrophobic interactions from G90, V377 and A163 to the sidechain. The last three residues that make this interaction are highly conserved among amino acid dehydrogenases. <ref name="1bgv" /> | <scene name='User:Cameron_Evans/Sandbox_1/1bgv_spec_pocket/2'>Specific interactions of ''Clostridium symbiosum'' GluDH to Glu</scene> are made up of polar interactions from K89 and S380 (to the gamma carbonyl) and hydrophobic interactions from G90, V377 and A163 to the sidechain. The last three residues that make this interaction are highly conserved among amino acid dehydrogenases. <ref name="1bgv" /> | ||
Furthermore, K113 makes specific contact with the alpha carboxyl and K90 the gamma carboxyl of the substrate.<ref name=1hwx /> | |||
Cofactor? | Cofactor? | ||