Isocitrate dehydrogenase: Difference between revisions
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== '''Structure:'''== | == '''Structure:'''== | ||
Isocitrate dehydrogenase is SCOP classified as an alpha beta structure. Its secondary composition consists of mainly alpha helices and beta sheets which are arranged into three layer alpha beta alpha sandwich structures. The entire protein consists of two side by side sandwich structures that face opposite directions. This then causes the proteins two active sites to face opposite directions. These two groups make up the A and B subunits of isocitrate dehydrogenase.In human isocitrate dehydrogenase there are 4 subunits. | Isocitrate dehydrogenase is SCOP classified as an alpha beta structure. Its secondary composition consists of mainly alpha helices and beta sheets which are arranged into three layer alpha beta alpha <scene name='Michael_nobbe_sandbox_2/Alpha_beta_sandwich/1'>sandwich structures.</scene>. The entire protein consists of two side by side sandwich structures that face opposite directions. This then causes the proteins two active sites to face opposite directions. These two groups make up the A and B subunits of isocitrate dehydrogenase.In human isocitrate dehydrogenase there are 4 subunits. | ||
{{STRUCTURE_1t0l | PDB=1t0l | SCENE= }} | {{STRUCTURE_1t0l | PDB=1t0l | SCENE= }} | ||