Collagen Structure & Function: Difference between revisions
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==Collagen-Related Disorders== | ==Collagen-Related Disorders== | ||
There are currently close to 30 different types of collagen that have been identified. The most abundant type of collagen present in the human body is that of Type I. | There are currently close to 30 different types of collagen that have been identified. The most abundant type of collagen present in the human body is that of Type I with significant amounts of Type II,III and IV also accounted for. | ||
*Type I- found in bones,tendons,organs | *Type I- found in bones,tendons,organs | ||
*Type II-found mainly in cartilage | *Type II-found mainly in cartilage | ||
*Type III-found mainly in reticular fibres | *Type III-found mainly in reticular fibres | ||
*Type IV- | *Type IV-found in the basement membrane of cell membranes | ||
*Type V- | *Type V-found in hair | ||
{{STRUCTURE_1cag | PDB=1cag | SCENE= }} | {{STRUCTURE_1cag | PDB=1cag | SCENE= }} |
Revision as of 04:44, 22 March 2010
CollagenCollagen
IntroductionIntroduction
Collagen is a member of a naturally occurring protein family. In nature is is found in animals and is responsible for a variety of biological functions.
Molecular StructureMolecular Structure
Collagen takes the form of a triple helix which is stabilized by hydrogen bonding. Each helix is enclosed by a hydration cylinder.
Collagen-Related DisordersCollagen-Related Disorders
There are currently close to 30 different types of collagen that have been identified. The most abundant type of collagen present in the human body is that of Type I with significant amounts of Type II,III and IV also accounted for.
- Type I- found in bones,tendons,organs
- Type II-found mainly in cartilage
- Type III-found mainly in reticular fibres
- Type IV-found in the basement membrane of cell membranes
- Type V-found in hair
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1cag, resolution 1.85Å () | |||||||
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Ligands: | |||||||
Non-Standard Residues: | |||||||
Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
Coordinates: | save as pdb, mmCIF, xml |