Succinate Dehydrogenase: Difference between revisions

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[[Image:S.D.Oxidation_of_Succinate_E2.gif]]
[[Image:S.D.Oxidation_of_Succinate_E2.gif]]


'''Image 1: Oxidation of succinate to fumarate through E2 elimination'''
'''Image 1: Oxidation of succinate to fumarate through E2 elimination''' (from Adamandalex in ''Wikimedia Commons'' http://en.wikipedia.org/wiki/File:S.D.Oxidation_of_Succinate_E2.gif).


In the proposed E1cb mechanism, the deprotonation leads to the formation of an enolate intermediate; FAD then removes the hydride, as shown in Image 2 <ref>PMID:16950775</ref>.
In the proposed E1cb mechanism, the deprotonation leads to the formation of an enolate intermediate; FAD then removes the hydride, as shown in Image 2 <ref>PMID:16950775</ref>.
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[[Image:S.D.Oxidation_of_Succinate_E1cb.gif]]
[[Image:S.D.Oxidation_of_Succinate_E1cb.gif]]


'''Image 2: Oxidation of succinate to fumarate via E1cb elimination'''
'''Image 2: Oxidation of succinate to fumarate via E1cb elimination''' (from Adamandalex in ''Wikimedia Commons'' http://en.wikipedia.org/wiki/File:S.D.Oxidation_of_Succinate_E1cb.gif).


====Ubiquinone reduction====
====Ubiquinone reduction====
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[[Image:QuinoneMechanism.gif]]
[[Image:QuinoneMechanism.gif]]


'''Image 3: Reduction of ubiquinone to ubiquinol'''
'''Image 3: Reduction of ubiquinone to ubiquinol''' (from Adamandalex in ''Wikimedia Commons'' http://en.wikipedia.org/wiki/File:QuinoneMechanism.gif).




===References:===
===References===
<references/>
<references/>

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