Triose Phosphate Isomerase Structure & Mechanism: Difference between revisions

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Triose phosphate isomerase (TIM) is a crucial enzyme in the glycolytic pathway.  <scene name='Christian_Krenk_Sandbox/Nc_rainbow/1'>TIM</scene> reversibly converts the aldose Glyceraldehyde-3-phosphate (GASP) to the ketose Dihydroxyacetone phosphate (DHAP).  The interconversion proceeds by an enediol intermediate.
Triose phosphate isomerase (TIM)<ref>PMID:16511037</ref> (PDB [[1wyi]]) is a crucial enzyme in the glycolytic pathway.  <scene name='Christian_Krenk_Sandbox/Nc_rainbow/1'>TIM</scene> reversibly converts the aldose Glyceraldehyde-3-phosphate (GASP) to the ketose Dihydroxyacetone phosphate (DHAP).  The interconversion proceeds by an enediol intermediate.


==Structural Characteristics of TIM==
==Structural Characteristics of TIM==

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Christian Krenk, David Canner, Diamond B. Reese, Michal Harel, Jane S. Richardson, Alexander Berchansky