3kn2: Difference between revisions

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'''Unreleased structure'''
{{Seed}}
[[Image:3kn2.jpg|left|200px]]


The entry 3kn2 is ON HOLD
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{{STRUCTURE_3kn2|  PDB=3kn2 |  SCENE=  }}


Authors: Nair, L.G., Sannigrahi, M., Pinto, P., Bogen, S., Chen, K.X., Njoroge, G., Prongay, A.
===HCV NS3 Protease Domain with ketoamide inhibitor===


Description: HCV NS3 Protease Domain with ketoamide inhibitor


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 13 13:32:28 2010''
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{{ABSTRACT_PUBMED_20004570}}
 
==About this Structure==
3KN2 is a 4 chains structure with sequences from [http://en.wikipedia.org/wiki/Hepatitis_c_virus_subtype_1a Hepatitis c virus subtype 1a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KN2 OCA].
 
==Reference==
<ref group="xtra">PMID:20004570</ref><references group="xtra"/>
[[Category: Hepatitis c virus subtype 1a]]
[[Category: Bogen, S.]]
[[Category: Chen, K X.]]
[[Category: Nair, L G.]]
[[Category: Njoroge, G.]]
[[Category: Pinto, P.]]
[[Category: Prongay, A.]]
[[Category: Sannigrahi, M.]]
[[Category: Atp-binding]]
[[Category: Capsid protein]]
[[Category: Envelope protein]]
[[Category: Helicase]]
[[Category: Hepatitis c virus]]
[[Category: Host membrane]]
[[Category: Hydrolase]]
[[Category: Ketoamide inhibitor]]
[[Category: Membrane]]
[[Category: Ns3 protease domain]]
[[Category: Nucleotide-binding]]
[[Category: Rna replication]]
[[Category: Serine protease]]
[[Category: Transmembrane]]
[[Category: Virion]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 20 16:01:44 2010''

Revision as of 17:01, 20 January 2010

File:3kn2.jpg

Template:STRUCTURE 3kn2

HCV NS3 Protease Domain with ketoamide inhibitorHCV NS3 Protease Domain with ketoamide inhibitor

Template:ABSTRACT PUBMED 20004570

About this StructureAbout this Structure

3KN2 is a 4 chains structure with sequences from Hepatitis c virus subtype 1a. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Nair LG, Sannigrahi M, Bogen S, Pinto P, Chen KX, Prongay A, Tong X, Cheng KC, Girijavallabhan V, George Njoroge F. P4 capped amides and lactams as HCV NS3 protease inhibitors with improved potency and DMPK profile. Bioorg Med Chem Lett. 2010 Jan 15;20(2):567-70. Epub 2009 Nov 22. PMID:20004570 doi:10.1016/j.bmcl.2009.11.094

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