3ivh: Difference between revisions

Revision as of 10:29, 6 January 2010

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File:3ivh.jpg

Template:STRUCTURE 3ivh

Design and Synthesis of Potent BACE-1 Inhibitors with Cellular Activity: Structure-Activity Relationship of P1 SubstituentsDesign and Synthesis of Potent BACE-1 Inhibitors with Cellular Activity: Structure-Activity Relationship of P1 Substituents

Template:ABSTRACT PUBMED 19811916

About this StructureAbout this Structure

3IVH is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

^{[xtra 1]}

↑ Sealy JM, Truong AP, Tso L, Probst GD, Aquino J, Hom RK, Jagodzinska BM, Dressen D, Wone DW, Brogley L, John V, Tung JS, Pleiss MA, Tucker JA, Konradi AW, Dappen MS, Toth G, Pan H, Ruslim L, Miller J, Bova MP, Sinha S, Quinn KP, Sauer JM. Design and synthesis of cell potent BACE-1 inhibitors: structure-activity relationship of P1' substituents. Bioorg Med Chem Lett. 2009 Nov 15;19(22):6386-91. Epub 2009 Sep 19. PMID:19811916 doi:10.1016/j.bmcl.2009.09.061

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OCA

[1] Sealy JM, Truong AP, Tso L, Probst GD, Aquino J, Hom RK, Jagodzinska BM, Dressen D, Wone DW, Brogley L, John V, Tung JS, Pleiss MA, Tucker JA, Konradi AW, Dappen MS, Toth G, Pan H, Ruslim L, Miller J, Bova MP, Sinha S, Quinn KP, Sauer JM. Design and synthesis of cell potent BACE-1 inhibitors: structure-activity relationship of P1' substituents. Bioorg Med Chem Lett. 2009 Nov 15;19(22):6386-91. Epub 2009 Sep 19. PMID:19811916 doi:10.1016/j.bmcl.2009.09.061

[xtra 1]

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-'''Unreleased structure'''
+{{Seed}}
+[[Image:3ivh.jpg|left|200px]]
-The entry 3ivh is ON HOLD  until Paper Publication
+<!--
+The line below this paragraph, containing "STRUCTURE_3ivh", creates the "Structure Box" on the page.
+You may change the PDB parameter (which sets the PDB file loaded into the applet)
+or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+or leave the SCENE parameter empty for the default display.
+-->
+{{STRUCTURE_3ivh|  PDB=3ivh  |  SCENE=  }}
-Authors: Pan, H.
+===Design and Synthesis of Potent BACE-1 Inhibitors with Cellular Activity: Structure-Activity Relationship of P1 Substituents===
-Description: Design and Synthesis of Potent BACE-1 Inhibitors with Cellular Activity: Structure-Activity Relationship of P1 Substituents
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 18 18:47:37 2009''
+<!--
+The line below this paragraph, {{ABSTRACT_PUBMED_19811916}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 19811916 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_19811916}}
+==About this Structure==
+IVH is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IVH OCA].
+==Reference==
+<ref group="xtra">PMID:19811916</ref><references group="xtra"/>
+[[Category: Homo sapiens]]
+[[Category: Memapsin 2]]
+[[Category: Pan, H.]]
+[[Category: Alternative splicing]]
+[[Category: Alzheimer's disease]]
+[[Category: Aspartyl protease]]
+[[Category: Bace-1 inhibitor]]
+[[Category: Disulfide bond]]
+[[Category: Glycoprotein]]
+[[Category: Hydrolase]]
+[[Category: Membrane]]
+[[Category: Polymorphism]]
+[[Category: Protease]]
+[[Category: Structure-based drug design]]
+[[Category: Transmembrane]]
+[[Category: Zymogen]]
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan  6 09:29:00 2010''