3hs4: Difference between revisions

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'''Unreleased structure'''
{{Seed}}
[[Image:3hs4.jpg|left|200px]]


The entry 3hs4 is ON HOLD until Paper Publication
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{{STRUCTURE_3hs4|  PDB=3hs4  |  SCENE=  }}


Authors: Robbins, A.H., Genis, C., Domsic, J., Sippel, K.H., Agbandje-McKenna, M., McKenna, R.
===Human carbonic anhydrase II complexed with acetazolamide===


Description: Human carbonic anhydrase II complexed with acetazolamide


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 5 09:45:13 2009''
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{{ABSTRACT_PUBMED_19851004}}
 
==Disease==
Known disease associated with this structure: Osteopetrosis, autosomal recessive 3, with renal tubular acidosis OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=611492 611492]]
 
==About this Structure==
3HS4 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HS4 OCA].
 
==Reference==
<ref group="xtra">PMID:19851004</ref><ref group="xtra">PMID:2128470</ref><references group="xtra"/>
[[Category: Carbonate dehydratase]]
[[Category: Homo sapiens]]
[[Category: Agbandje-McKenna, M.]]
[[Category: Domsic, J.]]
[[Category: Genis, C.]]
[[Category: McKenna, R.]]
[[Category: Robbins, A H.]]
[[Category: Sippel, K H.]]
[[Category: 4-thiadiazole-2-sulfonamide]]
[[Category: 5-acetamido-1]]
[[Category: Acetazolamide]]
[[Category: Acetylation]]
[[Category: Ca 2]]
[[Category: Ca ii]]
[[Category: Carbonic anhydrase 2]]
[[Category: Carbonic anhydrase ii]]
[[Category: Cytoplasm]]
[[Category: Disease mutation]]
[[Category: Lyase]]
[[Category: Metal-binding]]
[[Category: Polymorphism]]
[[Category: Zinc]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 9 15:09:52 2009''

Revision as of 16:09, 9 December 2009

File:3hs4.jpg

Template:STRUCTURE 3hs4

Human carbonic anhydrase II complexed with acetazolamideHuman carbonic anhydrase II complexed with acetazolamide

Template:ABSTRACT PUBMED 19851004

DiseaseDisease

Known disease associated with this structure: Osteopetrosis, autosomal recessive 3, with renal tubular acidosis OMIM:[611492]

About this StructureAbout this Structure

3HS4 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1][xtra 2]

  1. ↑ Sippel KH, Robbins AH, Domsic J, Genis C, Agbandje-McKenna M, McKenna R. High-resolution structure of human carbonic anhydrase II complexed with acetazolamide reveals insights into inhibitor drug design. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Oct 1;65(Pt, 10):992-5. Epub 2009 Sep 25. PMID:19851004 doi:10.1107/S1744309109036665
  2. ↑ Vidgren J, Liljas A, Walker NP. Refined structure of the acetazolamide complex of human carbonic anhydrase II at 1.9 A. Int J Biol Macromol. 1990 Dec;12(6):342-4. PMID:2128470

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