3h2l: Difference between revisions

Revision as of 15:59, 9 December 2009

This article has been automatically seeded. Changes to this page should pertain to the PDB entry only and not to the protein or biomolecule in general.

File:3h2l.jpg

Template:STRUCTURE 3h2l

Crystal structure of HCV NS5B polymerase in complex with a novel bicyclic dihydro-pyridinone inhibitorCrystal structure of HCV NS5B polymerase in complex with a novel bicyclic dihydro-pyridinone inhibitor

Template:ABSTRACT PUBMED 19818610

About this StructureAbout this Structure

3H2L is a 2 chains structure of sequences from Viruses. Full crystallographic information is available from OCA.

ReferenceReference

^{[xtra 1]}

↑ Ruebsam F, Murphy DE, Tran CV, Li LS, Zhao J, Dragovich PS, McGuire HM, Xiang AX, Sun Z, Ayida BK, Blazel JK, Kim SH, Zhou Y, Han Q, Kissinger CR, Webber SE, Showalter RE, Shah AM, Tsan M, Patel RA, Thompson PA, Lebrun LA, Hou HJ, Kamran R, Sergeeva MV, Bartkowski DM, Nolan TG, Norris DA, Khandurina J, Brooks J, Okamoto E, Kirkovsky L. Discovery of tricyclic 5,6-dihydro-1H-pyridin-2-ones as novel, potent, and orally bioavailable inhibitors of HCV NS5B polymerase. Bioorg Med Chem Lett. 2009 Nov 15;19(22):6404-12. Epub 2009 Sep 17. PMID:19818610 doi:10.1016/j.bmcl.2009.09.045

Page seeded by OCA on Wed Dec 9 14:59:46 2009

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

[1] Ruebsam F, Murphy DE, Tran CV, Li LS, Zhao J, Dragovich PS, McGuire HM, Xiang AX, Sun Z, Ayida BK, Blazel JK, Kim SH, Zhou Y, Han Q, Kissinger CR, Webber SE, Showalter RE, Shah AM, Tsan M, Patel RA, Thompson PA, Lebrun LA, Hou HJ, Kamran R, Sergeeva MV, Bartkowski DM, Nolan TG, Norris DA, Khandurina J, Brooks J, Okamoto E, Kirkovsky L. Discovery of tricyclic 5,6-dihydro-1H-pyridin-2-ones as novel, potent, and orally bioavailable inhibitors of HCV NS5B polymerase. Bioorg Med Chem Lett. 2009 Nov 15;19(22):6404-12. Epub 2009 Sep 17. PMID:19818610 doi:10.1016/j.bmcl.2009.09.045

[xtra 1]

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+{{Seed}}
+[[Image:3h2l.jpg|left|200px]]
-The entry 3h2l is ON HOLD  until Paper Publication
+<!--
+The line below this paragraph, containing "STRUCTURE_3h2l", creates the "Structure Box" on the page.
+You may change the PDB parameter (which sets the PDB file loaded into the applet)
+or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+or leave the SCENE parameter empty for the default display.
+-->
+{{STRUCTURE_3h2l|  PDB=3h2l  |  SCENE=  }}
-Authors: Han, Q., Showalter, R.E., Zhou, Q., Kissinger, C.R.
+===Crystal structure of HCV NS5B polymerase in complex with a novel bicyclic dihydro-pyridinone inhibitor===
-Description: Crystal structure of HCV NS5B polymerase in complex with a novel bicyclic dihydro-pyridinone inhibitor
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 13 09:34:50 2009''
+<!--
+The line below this paragraph, {{ABSTRACT_PUBMED_19818610}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 19818610 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_19818610}}
+==About this Structure==
+H2L is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Viruses Viruses]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H2L OCA].
+==Reference==
+<ref group="xtra">PMID:19818610</ref><references group="xtra"/>
+[[Category: RNA-directed RNA polymerase]]
+[[Category: Viruses]]
+[[Category: Han, Q.]]
+[[Category: Kissinger, C R.]]
+[[Category: Showalter, R E.]]
+[[Category: Zhou, Q.]]
+[[Category: Acetylation]]
+[[Category: Apoptosis]]
+[[Category: Atp-binding]]
+[[Category: Hepatitis c]]
+[[Category: Protein-ligand complex]]
+[[Category: Rna replication]]
+[[Category: Rna-binding]]
+[[Category: Rna-directed rna polymerase]]
+[[Category: Transferase]]
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec  9 14:59:46 2009''